Lege Artis Medicinae - 2010;20(03-04)

Lege Artis Medicinae

MARCH 20, 2010

Lege Artis Medicinae

MARCH 20, 2010

Lege Artis Medicinae

MARCH 20, 2010

[Neuroendocrine background of atherosclerosis and cardiovascular damages in durable stress]

MOLNÁR Ildikó

[Chronic stress is associated with increased levels of cortisol and catecholamines as well as with an enhanced activity of the sympathico-sensory nervous system. These neuroendocrine events influence both directly and indirectly the lipid and glucose metabolism as well as inflammatory immune reactions. Stress effects directly cause vascular damage and atherosclerosis via the renin-angiotensin system (RAS). Besides RAS, activities of monocytes/macrophages and the sympathico-sensory nervous... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[Fungal infections of the lung]

SÁROSI Veronika, BALIKÓ Zoltán

[During the past years the frequency of pulmonary mycoses has increased; the most serious cases include Candida- and Aspergillus-infections. In this article, we discuss primarily the clinical manifestations of these infections, but we also mention the Pneumocystis jiroveci, Cryptococcus neoformans and Zygomycosis/ Mucormycosis infections. We describe the role of the chest physician in the diagnostic procedure and position the bronchoscopic examinations in the diagnostic algorythm.]

Lege Artis Medicinae

MARCH 20, 2010

[Several questions of medical treatments in polycystic ovary syndrome]

BAJNOK László

[Polycystic ovary syndrome is an endemic disease, thus its treatment is of great importance. In polycystic ovary syndrome, metformin decreases androgen levels, improves menstrual irregularity, hirsutism, ovulation ratio, and the efficiency of lifestyle interventions on visceral obesity, endothelial function and LDL-cholesterol level. It seems plausible to suppose that metformin decreases the incidence of diabetes in this group of patients. Metformin is superior to oral... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[A new era in the treatment of patients with type 2 diabetes - Significance of the incretin analogue liraglutide from an internist’s perspective]

FARSANG Csaba

[Therapy of patients with type-2 diabetes has two important features: in addition to the nonpharmacological approach (changes in lifestyle and diet, smoking cessation, physical exercise), pharmacological intervention is needed to reach the target level of blood sugar, and those of other cardiometabolic risk factors (blood pressure, body weight, lipids, uric acid). Unfortunately, it is a worldwide problem that only a small fraction of diabetic patients reach all these goals. This is why it is... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[The safety of rosiglitazone - Lessons from the RECORD study]

HALMOS Tamás

[The international RECORD study team evaluated the safety of the oral antidiabetic drug rosiglitazone, after contradictory reports of its unfavourable cardiovascular adverse effects, in combination with sulfonyureas and metformin. The drug didn’t increase cardiovascular morbidity and overall mortality compared with standard blood sugar lowering drugs. However, it increased the risk of heart failure, and, in women, the risk of limb fractures. Keeping in mind the strict contraindications, the... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[Report from a country in poor health]

VITRAI József, BAKACS Márta, JUHÁSZ Attila, KAPOSVÁRI Csilla, NAGY Csilla

Lege Artis Medicinae

MARCH 20, 2010

[Nebivolol: the long-acting, vasodilatator beta-blocker]

LÉGRÁDY Péter

[Nebivolol is a third-generation, long-acting, vasodilator beta-adrenoceptor-blocker with very high selectivity to beta-1 receptor. In addition to its efficient blood pressure lowering effect, results of previous trials have shown that nebivolol, which has a vasodilator effect and improves endothelial dysfunction, offers a safe, well-tolerable therapeutic option for elderly patients with heart failure, chronic pulmonary disease, diabetes, hyperlipidaemia and hypertension. It does not affect or... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[Examination of the parameters affecting restenosis using coronary stents]

TAKÁCS Tibor, BOGNÁR Eszter, DOBRÁNSZKY János

[Treatment of coronary artery stenoses has substantially changed; previous cardiac surgery methods have been replaced by percutaneous coronary interventions, especially coronary stent implantations. Nevertheless, stenonis can reoccur in the artery following stent implantation; this process is called in-stent restenosis. In the present study, we examined the technical characteristics of coronary stents that, if selected optimally, can reduce the frequency of in-stent restenoses. These... tovább »

Lege Artis Medicinae

MARCH 20, 2010

[The role of risk sharing in drug funding]

KALÓ Zoltán, VOKÓ Zoltán

[In order to make the pharmaceutical budget predictable, an internationally accepted approach of health insurance providers is to shift more and more financial risks to pharmaceutical companies. The major paradox of financial risk-sharing schemes is that increased mortality, poor therapeutic compliance, reduced access to healthcare services, decreasing quality of health care and lack of treatment reduce pharmaceutical spending. Consequently, payers have started to employ reimbursement schemes... tovább »

Lege Artis Medicinae

MARCH 20, 2010

Lege Artis Medicinae

MARCH 20, 2010

[Secondary hyperaldosteronism resulting from a feeding disorder]

TÓTH Géza, RÁCZ Károly, FŰTŐ László

[INTRODUCTION - A number of diseases can cause hyperreninaemia and secondary hyperaldosteronism due to the stimulation of the renin-angiotensin system (RAS). The authors present a case of a patient suffering from a feeding disorder, whose secondary hyperaldosteronism verified by hormone examinations recovered after resolution of the feeding disorder. CASE REPORT - The authors found that the patient, who had been on an extreme vegetarian diet and avioded all forms of common salt as well as... tovább »

Lege Artis Medicinae

MARCH 20, 2010

Lege Artis Medicinae

MARCH 20, 2010

[HuMánia – Voluntary Peer Training for Future Physicians]

HORVÁTH Dóra Anita, DOMBI Anna Zsófia, FÉSŰS Szilvia, ROSTA Eszter Andrea, SÁNDOR Zsuzsanna, HEGEDŰS Katalin