Clinical Neuroscience

JULY 29, 1952

[Fundus examinations in connection with electrohock]

KLIMES Károly, ERŐSS Sándor

[The introduction and use of cumulative electroshock (ES) in our clinic, in addition to the therapeutic results, has also provided an opportunity to further investigate the basic and concomitant phenomena of the spasm mechanism. In this brief, quasi-preliminary report, we describe the ocular fundus lesions associated with spasm. As the essence of shock therapy is seen by many authors (Abély, Delay, Morin, Gastant, Cain) in the stimulation of the diencephalon, and Krienberg and Eberhardt have drawn attention to the fundamental importance of cerebral blood circulation in the mechanism of shock, the study of the orbital vessels of the fundus is of prime importance. The behaviour of the fundus blood vessels provides an analogous picture of the probable identical behaviour of the cerebral blood vessels, and the vasovegetatively congruent state of the pupils and fundus blood vessels also provides information on the fluctuations of the vegetative tone.]

Clinical Neuroscience

MARCH 23, 1950

[New aspects of Friedreich's disease]


[4 clinical observations of Friedreich's disease. 3 male, 1 female: three "pure" forms, one with amyotrophic lat. sclerosis. Heredofamilial trait in 3 cases: two patients had pes excavatus in the brother, the second patient had Dupuytren's contacture of the little finger. The 3rd case had a marked myocardial laesio; this was absent in the others. This therefore does not support the hypothesis that myocarditis and neurological lesions are caused by a common toxic agent.]

Lege Artis Medicinae

OCTOBER 01, 2000

[Antibacterial therapy: 2000 balance and perspectives]


[Following a brief history of antibacterial therapy and evaluating the achievements and damages occurred, authors focus on today's problems and the following statements are made: Principles of treatment are clearly defined, however the choice of antibiotics may vary in time and in regions according to the differences in bacterial resistance. Antibacterials of the last decade (III-IV. generation fluoroquinolones, streptogramins, oxazolidinones, new vancomycine analogues) are intended to be effective against multiresistant Gram-positive cocci. Beside bacterial resistance, the most difficult therapeutic problems are the infections in the immunocompromised patients. The role of infection in the pathogenesis of certain diseases, e.g. ventricular/duodenal ulcer and probably atherosclerosis, has only recently been discovered; here new prospects may open for antibacterials. Data of the antibiotic utilization in Hungary show radical changes in the last years. Conclusion: the immense power of antibiotics still has its limits: to conquer bacterial disease successfully the intelligent combination of antibiosis, asepsis and immunization are required. ]

Lege Artis Medicinae

OCTOBER 01, 2000

[The role of MR angiography in the examination of intracranial aneurysms: A comparative study]

P. Nagy Zoltán, BAJZIK Gábor , BOGNER Péter, BERÉNYI Ervin, SZÁSZ Krisztina, KOPA János, REPA Imre

[MR imaging has recently emerged for visual representation of blood vessel structures as well. With MR angiography (MRA), appropriate diagnosis can be established for a number of pathologies involving the arteries and veins. In this report, authors analyse the significance of MR and MRA examinations in the diagnostics of intracranial aneurysms of 87 cases, comparing these procedures with results obtained by digital subtraction angiography (DSA), which is regarded as the gold standard method. In 52 patients where surgical intervention was performed, intraoperative findings were used as control. MR - MR angiographic examination was very sensitive in detecting aneurysms larger than 3 mm (98%), the rate of depicting smaller aneurysms proved to be lower (56%), the overall sensitivity was 79%. MRA is an excellent non invasive diagnostic tool in the examination of intracranial aneurysms. The method can not replace catheter angiography completely but its application is justified and useful in many cases. Occasionally, aneurysms not seen on DSA can be depicted with MR angiography. ]

Journal of Nursing Theory and Practice

AUGUST 30, 2020

[Role of Atrial Fibrillation in Stroke Prevalence: Implementation of CHA2DS2 – Vasc Risk Stratifi­cation Scale]

PAPP László, VIDA Nóra, BENGŐ Szilvia, KIS Tamás , GAÁL Gabriella, PETŐ Zsófia

[Introduction: Stroke is one of the leading causes of death and disability, therefore is an important public health concern. 20% of ischaemic cerebrovascular diseases are casued by cardiac-related embolism, wiith non-valvular atrial fibrillation (AF) as a major cause, and results in approximately 3-5-fold risk improvement. The aim of this study is to introduce the CHADS2-VASc scoring system, as an important tool in the estimation of stroke risk in AF patients. Recognition of AF and initiation of adequate therapy is a crucial step in the prevention of serious complications. The best-known indexes for AF’s vascular effects are HAS-BLED and CHADS2-VASc. According to European Society of Cardiology, CHADS2-VASc is recommended to use in every AF case with stroke risk, when direct anticoagulant therapy could be implemented. A nurse can work on stroke risk reduction among AF patients in various levels and competences. Primary prevention and health promotion is a responsibility for every health care worker, but at the same time, Advenced Practice Nurse could have a role either in diagnostics or initiating proper therapy.]