Lege Artis Medicinae - 2009;19(06-07)

Lege Artis Medicinae

JULY 27, 2009

[Melatonin, sleep and the circadian rhythm: theoretical considerations and their chronopharmacological applications ]

BÓDIZS Róbert

[The predictive homeostasis of living organisms is an anticipatory adaptation to rhythmical environmental changes. A good example for this is the circadian rhythm preparing the organism for the alternation of day and night. The circadian rhythm of melatonin production anticipates the timing and duration of nocturnal sleep of human subjects. It also induces a sleep-like stimulusprocessing mode of the brain and - in case of adequate environmental circumstances - a soporific and in part, a... tovább »

Lege Artis Medicinae

JULY 27, 2009

[Combination of leflunomide and biologic agents in the treatment of rheumatoid arthritis]

SZŰCS Gabriella

[Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that leads to progressive joint destruction, functional disability and extra-articular complications. The initial approach to treatment of RA begins with the diagnosis, estimation of patient’s prognosis and the implementation of a therapeutic plan. Most important is early and aggressive treatment with disease-modifying antirheumatic drugs (DMARDs). Among the different protocols, combination therapies including methotrexate... tovább »

Lege Artis Medicinae

JULY 27, 2009

[Original and generic drugs: Research, efficacy, utilization, and financing ]

NOSZÁL Béla

[Starting from the definition of medicinal drugs, this paper covers the terms of original, active principles, original and generic drugs, and their distinctive and identical properties. It also surveys the fundamentals of drug-marketing authorization, criteria of therapeutic and bioequivalence, pharmaceutical and pharmacokinetic equivalence, and development possibilities of generic drugs.]

Lege Artis Medicinae

JULY 27, 2009

Lege Artis Medicinae

JULY 27, 2009

[Prevalence and potential predictors of morbidity among hungarian female physicians]

GYŐRFFY Zsuzsa, ÁDÁM Szilvia, KOPP Mária

[BACKGROUND - We explored the general health status of physicians in Hungary using a nationwide sample. Based on international and Hungarian literature, we hypothesised that the prevalence of psychiatric and somatic morbidity is higher among female physicians in Hungary compared to the normative population. SUBJECTS AND METHODS - The objective of our cross-sectional research was to study the morbidity of Hungarian female physicians as well as to analyse background factors. Data for this... tovább »

Lege Artis Medicinae

JULY 27, 2009

[What worries Hungarian men? - Characteristics of masculine gender role stress]

SUSÁNSZKY Anna, SUSÁNSZKY Éva, KOPP Mária

[INTRODUCTION - The aim of this study was to establish the characteristics of stress associated with male gender role and its relationship to health and to risk behaviours among Hungarian men. SUBJECTS AND METHODS - The present analysis is based on data of the Hungarostudy 2006 survey. Forty-one percent of the participants were men. Eighty nine percent of the male respondents completed the Eisler-Skidmore Masculine Gender Role Stress Scale; data of 1764 persons were analyzed. RESULTS - Anxiety... tovább »

Lege Artis Medicinae

JULY 27, 2009