Lege Artis Medicinae - 2009;19(04-05)

Lege Artis Medicinae

JUNE 10, 2009

[Focus on the diagnosis and therapy of chronic cough]

SZILASI Mária

[Cough by itself is not a disease but a part of a complex defense mechanism protecting from harmful materials entering the airways and cleaning the lungs and airways from potentially harmful materials. Normally, cough is accompanied by other defense mechanisms (bronchoconstriction and secretion of sputum) that increase the effectiveness of cough. Cough generally is caused by intrapulmonary disorders, but may be related to extrapulmonary lesions that are not easy to diagnose. In every case, an... tovább »

Lege Artis Medicinae

JUNE 10, 2009

[Tumor necrosis factor-alpha blockade: adverse clinical consequences and safety issues]

MŰZES Györgyi

[The pleiotropic cytokine tumor necrosis factor (TNF)-α seems to be fundamentally involved in the pathogenesis of a variety of immune-mediated (partly autoimmune) chronic inflammatory disorders; therefore, its blockade has allowed a remarkable advance in treatment strategies. Safety and tolerability profile of TNF-antagonists is generally favorable, their overall risk/benefit ratio is definitely positive. Possible adverse consequences related to TNF-α blocking monoclonal antibodies and soluble... tovább »

Lege Artis Medicinae

JUNE 10, 2009

[Necessity of a shift in attitudes in the judgment and therapy of skin and soft-tissue infections]

SZALKA András

[Skin and soft-tissue infections are defined as infections of the epidermis, dermis, or subcutan tissue. They are among the most common human bacterial infections observed in clinical practice. It has also been shown that the incidence of skin and soft-tissue infections is increasing. This has been attributed to several factors, including increasing population age, surgical wounds related to more invasive surgery in the ageing population, obesity, malnutrition, diabetes, peripheral vascular... tovább »

Lege Artis Medicinae

JUNE 10, 2009

[Long-term management of vascularly decompensated hepatic cirrhosis]

KISS Krisztina, KISS János Tibor, KISS Zsófia, GROSZ Andrea, NEMESÁNSZKY Elemér, BALÁZS Csaba

Lege Artis Medicinae

JUNE 10, 2009

[Enigma abdominalis - superior mesenteric artery syndrome]

SCHNABEL Róbert, G. TÓTH Kinga, BIRKÁS Dezső, PALIK Éva, BOGNÁR Gábor

[INTRODUCTION - Superior mesenteric artery syndrome is caused by vascular compression of the inferior transverse part of the duodenum due to the anomalous course of the superior mesenteric artery and/or a cranial shortening of the ligament of Treitz. Clinical caracteristics include postprandial epigastric pain, nausea, vomiting of bile, slow passage in the gastroduodenal passage, and as a consequence of the above, pernicious weight loss. CASE REPORT - In the case of a 35-year old woman with... tovább »

Lege Artis Medicinae

JUNE 10, 2009

[Isolated anal form of Crohn’s disease with an extensive perianal septic complication]

DOBÓ István, JÓSVAY János

[INTRODUCTION - Perianal manifestations of Crohn’s disease are common. Treatment of advanced complications like strictures and incontinence may require a radical surgical intervention. We present a case of an extremely rare manifestation of Crohn’s disease. The disease localized exclusively to the anal canal for more than twenty years was complicated by an extensive perianal septic lesion. Besides our own surgical strategy, we discuss in detail other therapeutic options for perianal septic... tovább »

Lege Artis Medicinae

JUNE 10, 2009

[Successful treatment of chronic hepatitis C infection accompanied by rare but reversible adverse effects]

ERŐSS Bálint Mihály, NEMESÁNSZKY Elemér

[INTRODUCTION - In absence of signs and symptoms characteristic of chronic hepatic disease caused by hepatitis C viral infection, its diagnosis is generally suggested by abnormal liver function tests. If viral serological activity is confirmed, combined antiviral treatment (pegylated interferon plus ribavirin) has to be considered. Antiviral treatment is accompanied by several, usually reversible adverse effects. CASE REPORT - The 62 year-old woman has had waveringly abnormal liver function... tovább »

Lege Artis Medicinae

JUNE 10, 2009