Lege Artis Medicinae - 2009;19(01)

Lege Artis Medicinae

JANUARY 27, 2009

Lege Artis Medicinae

JANUARY 27, 2009

[Importance of statin therapy in stroke prevention]

KÁPOSZTA Zoltán, RÁCZ Klára

[Stroke is the third leading cause of death and a leading cause of major adult disability in developed countries. The annual incidence of hospitalized stroke varies between 400-500 per 100 000 inhabitants every year in Hungary. In the past decade, cholesterol lowering with 3- hydroxy-3-methylglutaryl-coenzyme A (HMGCoA) reductase inhibitors (statins) has proved to reduce risk of stroke in patients with and without coronary disease (CAD). In patients with CAD, statin therapy reduces the risk of... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

[New possibilities in the management of hepatocellular carcinoma]

DANK Magdolna

[The prognosis of primary hepatocellular carcinoma (HCC) has been poor until recently. Most patients are diagnosed at an advanced stage, with a poor liver function, thus therapeutic possibilities are limited. In high-risk patients, active surveillance and HCC screening is essential for early diagnosis. Experience with systemic chemotherapy has been disappointing with low response rates and high rates of adverse effects. Recently, novel treatment options have emerged, including the use of... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

[Ways and tools of the organism's defence in atherosclerosis - The mysterious HDL particle]

JAKAB Lajos

[Every type of injury elicits an immediate defending, preventing response in the living organism, which involves the whole organism’s participation. In case of a single effect, the events and symptoms together can be designated as “acute phase reaction syndrome”. The pathogenic constituents' effects on the arterial wall are, however, permanent, though varying in composition and intensity. The protecting reaction serving the prevention of the continuously arising vessel wall lesion is... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

Lege Artis Medicinae

JANUARY 27, 2009

[Rivaroxaban: a new and efficient direct factor Xa inhibitor anticoagulant]

BLASKÓ György

[Rivaroxaban is a directly acting, orally administrable selective inhibitor of the activated blood clotting factor X, which could replace low molecular weight heparins and oral coumarintype anticoagulants. It was registered by European (EMEA) and US authorities (FDA) for the prevention of venous thrombotic events in orthopedic surgery. It is being investigated in phase III studies for the treatment of established, symptomatic venous thrombosis, surgical thromboprophylaxis, prevention and... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

[Efficacy of peginterferon alfa-2a and -2b plus ribavirin in the routine treatment of patients with chronic hepatitis C]

TUSNÁDI Anna, SZABÓ Anna

[INTRODUCTION - Combination of peginterferon plus ribavirin is the standard treatment for chronic hepatitis C virus (HCV) infection. Two types of peginterferon are available. The aim of this retrospective study was to find out whether the choice of peginterferon influenced the patient’s chance of recovery. PATIENTS AND METHODS - Between 2004 and 2007, 142 patients with HCV genotype 1 hepatitis with or without cirrhosis (107 treatmentnaive, 35 previously treated) were treated with 180 ug/week... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

Lege Artis Medicinae

JANUARY 27, 2009

[Medicine-induced osteonecrosis of the jaw]

VASZILKÓ Mihály, CSÉPLŐ Krisztina, NÉMETH Zsolt, BARABÁS József, UJPÁL Márta

[INTRODUCTION - Bisphosphonates are often used in the treatment of osteoporosis and of certain tumors with bone defects. Thus their rare side effect, necrosis of the jaw becomes more and more frequent. CASE REPORT - Between September 2005 and March 2008 we have treated 40 patients with bisphosphonate induced osteonecrosis in the maxillofacial region at our hospital. From this group, we selected two cases where typical complications emerged. CONCLUSION - Based upon data from the international... tovább »

Lege Artis Medicinae

JANUARY 27, 2009

Lege Artis Medicinae

JANUARY 27, 2009

[Relationships in recovery, recovery in relationships]

SZABÓ József, GEREVICH József

[INTRODUCTION - Some of the recent researches based on analyses of autobiographies pointed out, that the quality and the quantity of our social relations are in connection with our life longevity, and the frequency of words referring social roles and integration gives a respective measurement possibility of it. Conception of the term “social words” had been introduced. The influence of the degree of social support to the recovery from alcohol addiction is also a well-known phenomenon. Based on... tovább »

Lege Artis Medicinae

JANUARY 27, 2009