Lege Artis Medicinae

[Medicine-induced osteonecrosis of the jaw]

VASZILKÓ Mihály, CSÉPLŐ Krisztina, NÉMETH Zsolt, BARABÁS József, UJPÁL Márta

JANUARY 27, 2009

Lege Artis Medicinae - 2009;19(01)

[INTRODUCTION - Bisphosphonates are often used in the treatment of osteoporosis and of certain tumors with bone defects. Thus their rare side effect, necrosis of the jaw becomes more and more frequent. CASE REPORT - Between September 2005 and March 2008 we have treated 40 patients with bisphosphonate induced osteonecrosis in the maxillofacial region at our hospital. From this group, we selected two cases where typical complications emerged. CONCLUSION - Based upon data from the international literature and on our own experiences, we would like to draw attention to the importance of prevention. If symptoms are emerging, referral to a specialized department prepared to the treatment of this condition is recommended.]

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