Clinical Oncology - 2021;8(1)

Clinical Oncology

FEBRUARY 28, 2021

[Comprehensive care of the carcinoma of the uterine cervix]

ÁROKSZÁLLÁSI Anita

[Cancer of the uterine cervix is a major world health problem for women. Yearly around half a million new cases are diagnosed with cervical cancer having leaded nearly 300,000 deaths in 2018 globally. In developed countries epidemiological data is improving due to the vaccination policy against “high risk” human papilloma viruses (hrHPV) and the population-based screening programs by cytology or hrHPV-testing. However, in developing regions the incidence and mortality data are still... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[SARS-CoV-2 infection-lung demage. Lung cancer and Covid-19 in the TERAVOLT clinical studys]

SZONDY Klára, FUTÁCSI Balázs, KIS Sándor

[Hopefully, towards the end of the Covid-19 pandemic, we intend to provide a brief overview of the infection, the pathogen, most effective treatment options, lung damage, and the results of TERAVOLT clinical trial, about patients with lung cancer, treated or not-treated, infected by SARS-CoV-2 virus. Tried to summarize the new diagnostic and therapy rules (bronchoscopy, chest x-ray, chest CT), and the potential new vaccinations. Authors provide a brief overview of the treatment of respiratory... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[The benefits of vaccination in risk groups]

BÉRES Zsuzsanna Katalin

[As the average age increases, the prevention of infectious diseases is of paramount importance, not just during a pandemic. In terms of volume and complications, pneumococcal and influenza infections are among the top 10 most common causes of death. Timely and properly applied vaccination is an effective weapon against both diseases. This fact is confirmed by several clinical trials. The advent of conjugate vaccination has been a milestone in the history of vaccination. It is important that... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[Treatment of cancer associated venous thromboembolism in the age of direct oral anticoagulants]

AY C, BEYER-WESTENDORF J, PABINGER I

[Anticoagulation for cancer-associated venous thromboembolism (VTE) can be challenging due to complications-including bleeding and potential drug-drug interactions with chemotherapy-associated with vitamin K antagonists and inconvenience of low-molecular-weight heparin (LMWH). Direct oral anticoagulants (DOACs) could partially overcome these issues, but until recently there were no large clinical trials assessing their efficacy and safety in cancer patients. This review summarizes clinical... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[(K)RAS mutant human cancers]

TÍMÁR József, RÁSÓ Erzsébet

[RAS mutation is the most frequent oncogenic alteration in human cancers and K-RAS is far the most frequently involved among the RAS family members followed by N-RAS. Beside the emblematic K-RAS mutant cancers, pancreatic-, colorectal- and lung adenocarcinomas, urogenital cancers are also belong to this family of malignancies. It is important that K-RAS mutation frequencies are relatively stable around the world in various cancer types with one exeption: lung adenocarcinoma. The variant allele... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[Rehabilitation of cancer patients]

DANK Magdolna, PÉNTEK Irén, JUHÁSZ Ágnes, HAJDÚ Anett

[In our country, the number of neoplastic diseases is constantly increasing. Based on the KSH data 376,709 people had neoplastic diseases in 2017. The disease is a long-term, chronic process, and the physical burden caused by treatments makes it difficult to maintain the physical and mental balance of patients. The quality of life of the neoplastic diseases patient changes, his ability to work will be reduced, his role in the family will be changed, his physical and emotional strength. These... tovább »

Clinical Oncology

FEBRUARY 28, 2021

[Promising Radiotherapy techniques at the beginning of clinical implementation: microbeam- and FLASH therapy]

HIDEGHÉTY Katalin, TŐKÉS Tünde, POLANEK Róbert, SZABÓ Emília Rita

[Recent technical developments have enabled to implement ideas raised a few decades earlier. Extensive radiobiology experiments have demonstrated the potential clinical benefit from novel irradiation techniques with ultra high spatial and temporal resolution. A large number of preclinical studies have proven that instead of using homogeneous irradiation fields, arrays of tenths of millimeter beams spaced some hundred micrometer (microbeam radiotherapy – MRT) result in a significant increase in... tovább »