Lege Artis Medicinae - 2013;23(03-04)

Lege Artis Medicinae

APRIL 20, 2013

[Beyond the wrinkles: botulinum toxin for the treatment of focal dystonia]

KOVÁCS Tibor

[Botulinum toxin (BTX) is used in various fields including biological warfare as well as cosmetic applications. However, its ability to block neuromuscular transmission provides a unique option for the therapy of diseases associated with increased muscle tension. BTX is effective in both striated and smooth muscles, which makes it applicable for a number of clinical purposes beyond its cosmetic use. Clinical applications include treatment of focal dystonias, the most common form of which is... tovább »

Lege Artis Medicinae

APRIL 20, 2013

[The effect of obesity on cardiovascular diseases and the significance of the obesity paradox]

PARAGH György, JUHÁSZ Imre, FÜLÖP Péter

[Obesity represents a major health burden worldwide. Besides its growing prevalence, obesity contributes to the development of many cardiovascular diseases and thus increases the incidence of hypertension, diabetes, cardiomyopathy, heart failure, myocardial infarction, arrhythmias and stroke. Surprisingly, however, recent studies showed that in some cases obesity might improve survival and decrease the risk of mortality. This phenomenon has been named the obesity paradox. In this paper, we... tovább »

Lege Artis Medicinae

APRIL 20, 2013

[Apixaban: the newest oral anticoagulant in Hungary for the treatment of patients with atrial fibrillation]

BORBÉLY Attila, ÉDES István

[In the past few years a number of articles have been published on the new oral anticoagulants (Xa-factor inhibitors, thrombin inhibitors). These new agents are increasingly used in the daily clinical practice in Hungary. The new oral anticoagulants have been shown to be at least as effective in the prevention of stroke and systemic embolization related to non-valvular atrial fibrillation as K vitamin antagonists. Moreover, their use is safe, can be administered in a daily fixed dose and, even... tovább »

Lege Artis Medicinae

APRIL 20, 2013

[A new option in insulin therapy that decreases the risk of hypoglycaemia]

BECHER Péter, MÁJER Katalin, PATAI Árpád

[Insulin degludec is a novel, ultra-long acting basal insulin analogue with a safety and efficacy similar to those of insulin glargine. Its main advantage is its ability to significantly reduce hypoglycaemia, particularly nocturnal hypoglycaemia. We present in detail the results of the BEGIN clinical studies with degludec.]

Lege Artis Medicinae

APRIL 20, 2013

[Health-economic analysis of diseases related to disturbed neonatal adaptation: a cost of illness study]

BONCZ Imre, KOVÁCS L. Gábor, ERTL Tibor, ÁGOSTON István, MOLICS Bálint, BÓDIS József

[OBJECTIVES - The aim of our study is to perform a health-economic analysis of diseases related to disturbed neonatal adaptation by assessing the burden of health care costs in Hungary. DATA AND METHODS - Data were derived from the financial dataset of the National Health Insurance Fund Administration (OEP) covering year 2009. Four diseases were included in the analysis: polycystic ovary syndrome (E2820), retinopathy of prematurity (H3510), hyperstimulation of ovaries (N9810) and respiratory... tovább »

Lege Artis Medicinae

APRIL 20, 2013

[Detection of endemic MRSA colonisation in a retirement home]

STÁNITZ Éva, TOMPITY Tünde, UNGVÁRI Erika, PÁSZTI Judit

[Methycillin-resistant Staphylococcus aureus (MRSA) colonisation was proved in a retirement home. A resident of the social institution (a 83-year-old man) was hospitalised and was cared for in a ward where a patient positive for MRSA was treated. Screening tests of the above mentioned resident, one of his room-mates at the retirement home as well as three of the four nurses being on duty at the weekend when the man returned to the social institution from the hospital proved the presence of MRSA... tovább »