Lege Artis Medicinae

[The effect of obesity on cardiovascular diseases and the significance of the obesity paradox]

PARAGH György, JUHÁSZ Imre, FÜLÖP Péter

APRIL 20, 2013

Lege Artis Medicinae - 2013;23(03-04)

[Obesity represents a major health burden worldwide. Besides its growing prevalence, obesity contributes to the development of many cardiovascular diseases and thus increases the incidence of hypertension, diabetes, cardiomyopathy, heart failure, myocardial infarction, arrhythmias and stroke. Surprisingly, however, recent studies showed that in some cases obesity might improve survival and decrease the risk of mortality. This phenomenon has been named the obesity paradox. In this paper, we discuss the findings regarding this phenomenon and its possible biological explanations. We also draw the attention to the beneficial effects of individually tailored weight reduction therapy.]

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