Lege Artis Medicinae - 2012;22(10-11)

Lege Artis Medicinae

NOVEMBER 22, 2012

[The biological basis of screening: natural history of malignous tumours]

DÖBRŐSSY Lajos, KOVÁCS Attila, BUDAI András

[The development of malignous tumours is a prolonged, multistage process. The onset of clinical symptoms and subjective complaints is preceded by the preclinical detectable phase, during which the tumour does not cause any symptoms but it has some signs and can be detected by screening. Information on the tumour’s natural history is of practical importance for choosing the screening strategy. When evaluating screening results, the various biases related to biological reasons need to be taken... tovább »

Lege Artis Medicinae

NOVEMBER 22, 2012

[Hospital antibiotic stewardship 2012]

RÓKUSZ László

[The increasing resistance of hospital pathogens to antimicrobial drugs and the related morbidity and mortality is a worldwide problem. The development of new antimicrobial drugs is slow. Hospital antimicrobial stewardship is aimed to optimise antimicrobial therapy of hospitalised patients, improve patients’ outcome and prevent the development of resistance to antimicrobial agents. This review describes antibiotic stewardship in clinical practice.]

Lege Artis Medicinae

NOVEMBER 22, 2012

[Is postmenopausal hormone therapy suitable for cardiovascular prevention?]

LÁSZLÓ Ádám

[After menopause, coronary disease and infarction become increasingly common in women owing to estrogen deficiency. Therefore, hormon replacement therapy (HRT) had been widely used to prevent these problems and manage postmenopausal symptoms. In 2002, a large, randomised, placebo-controlled study reported that HRT was accompanied by serious side effects and was not suitable for cardiovascular prevention. However, subsequent re-alanyses of the data of this study and new studies in the past 10... tovább »

Lege Artis Medicinae

NOVEMBER 22, 2012

[The role of the DPP-4 inhibitor sitagliptin in the therapy of type 2 diabetes, in light of the new guidelines]

HIDVÉGI Tibor

[Type 2 diabetes has become a global public health problem, threatening the economies of all nations, as a consequence of rapid urbanisation, changing eating habits, sedentary lifestyle and obesity. Asian populations tend to develop diabetes at younger ages and lower body mass index compared with Caucasians. The latest guidelines of the American Diabetes Association and the European Association for the Study of Diabetes recommend lifestyle interventions as the first step for patients with newly... tovább »

Lege Artis Medicinae

NOVEMBER 22, 2012

[The sensor-augmented insulin pump and its use in clinical practice]

KÁNTOR Irén

[Diabetes is one of the most common chronic diseases. Technological advances provide increasingly refined tools for clinicians to manage type 1 and type 2 diabetes. Continuous subcutaneous insulin infusion (CSII), also known as insulin pump, allows for a sophisticated delivery of basal as well as bolus insulin. Continuous glucose monitoring helps patients and clinicians understand and manage changes in blood glucose trends and minute-to-minute blood glucose variablitiy. The sensor-augmented... tovább »

Lege Artis Medicinae

NOVEMBER 22, 2012

Lege Artis Medicinae

NOVEMBER 22, 2012