Lege Artis Medicinae - 2011;21(08-09)

Lege Artis Medicinae

SEPTEMBER 20, 2011

[Empirical versus preemptive antifungal therapy of invasive fungal infections in patients with oncohaematological diseases]

RÓKUSZ László

[Fungal infections present a significant problem among immunocompromised patients. The essence of empirical antifungal therapy is to collect data, physical signs and symptoms that confirm the clinically suspected invasive fungal infections and enable initiation of antifungal therapy. With the improvement of early diagnosis of invasive fungal infactions, the diagnosisdrived application of antifungal preparations has been re-evaluated. However, no consensus exists to date regarding preemptive... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

[The use of carvedilol following invasive interventions]

KOVÁCS Imre

[The primary goals of the treatment of AMI are to rapidly open - either mechanically or by thrombolysis - the blocked blood vessel and to keep it open. Restarting of the blood flow in blocked vessels results in an increased load in volume, pressure and metabolism in the blood vessel's supply area, which triggers the activation of a pathophysiological cascade. Pathophysiological processes accompanying the opening of the blood vessel include activation of catecholamines, RAS and neutrophils and... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

[The development of insulin treatment from discovery of insulin to analogue preparations]

KÁPLÁR Miklós, PARAGH György

[The discovery of insulin was a milestone in the treatment of diabetes mellitus. Animalderived (porcine and cattle) insulins available at the beginning were later replaced by human insulins. Recently, analogue insulins are the most widespreadly used. Besides the increase in the quantity and improvement in the quality of the insulin products, the growth of the treatment regimes is apparent, as well. That varies from the once-given daily basal insulin treatment added to oral antidiabetic drugs to... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

[Advantages of fixed combinations in the treatment of hypertensive patients]

FARSANG Csaba

[In 60-70% of patients with hypertension, a significant decrease in blood pressure can only be achieved by a combination of antihypertensive drugs. International as well as national guidelines emphasise the numerous advantages and the importance of combination treatment. Fixed combinations are particularly advantageous, as their use improves patients’ compliance. This paper summarises the available information on the possible combinations of the nine major antihypertensive drug groups... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

Lege Artis Medicinae

SEPTEMBER 20, 2011

[Experience with coenzyme Q10 in heart failure]

KOHUT László

[INTRODUCTION - The protein complex coenzyme Q10 (CoQ10) has a role in ATP production as a mitochondrial electron transport molecule, and it also has a strong antioxidant effect. Several studies have proved the correlation between the decrease in CoQ10 level and the severity of heart failure. Heart failure is a multifactorial syndrome, the development of which is greatly influenced by an abnormal energy metabolism. CASE REPORT - The 61-year-old woman developed heart failure after a myocardial... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

[Fourth-year medical students’ views about informal payment in Hungary]

HORVÁTH Ferenc, TEREBESSY András, BALÁZS Péter

[Introduction - Scientific evaluation from ethical, legal and economical aspects of gratuity (informal) payment in the Hungarian health care system was initiated first in the 1980s and was completed by the end of the 1990s. Since then, there are no unanswered scientific questions regarding the evaluation of this phenomenon; however, theoretical studies did not have any practical consequences. Healthcare policy has been experimenting with indirect initiatives, relying on the changing behaviour... tovább »

Lege Artis Medicinae

SEPTEMBER 20, 2011

Lege Artis Medicinae

SEPTEMBER 20, 2011

[The role of measuring galactomannan in the modern therapy of invasive aspergillosis]

SINKÓ János

[Invasive aspergillosis is a life threatening mycosis prevalent in groups of patients with specific risk factors. To establish the diagnosis a specimen for histological examination has to be obtained. However, the vast majority of patients are not suitable for biopsy or this procedure can only be performed late in the course of the disease. Current diagnostic workup is based on high resolution thoracic CT scans and serum galactomannan antigen testing. Antigen detection can either be used for... tovább »