Lege Artis Medicinae - 2000;10(09)

Lege Artis Medicinae

SEPTEMBER 01, 2000

[Bacteriophage therapy and prophylaxis; Renewal of earlier expectations]

MILCH Hedda

[Bacteriophages were discovered 84 years ago by the observation of a lysis of a bacterial culture. The aim of the earliest attempts was the therapeutic employment of bacteriophages. The experiments controlled unsatisfactorily, could not fulfill expecations and successful antibiotic testing resulted the rejection of bacteriophage therapy. Bacteriophages gained importance in biology in the 1950s, as model viruses in biological and genetic research. The decrease in the success of antibiotic... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[Newly discovered molecules the chemokines]

KŐHIDAI László, DÉRFALVY Beáta

[Chemokine research in the last decade has provided new results in several areas of biomedicine. Investigation and characterization of chemokines resulted in better understanding and modeling complex pathophysiological and immunological processes. Chemokine research opened up entirely new aspects on the defense against pathogenic agents as well as on the processes of inflammation and angiogenesis. With the amount of clinical data growing steadily, it is clear that chemokines could play very... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[Effect of calcium channel blocking drugs on the periodontal status of hospitalised patients]

KEGLEVICH Tibor, ZSIDRÓ Emese, BENEDEK Erika, BARNA István, SZEGEDI Zsolt, SCHWAB E. Richárd, GERA István

[Ca2+-channel blockers play crucial role in the chronic treatment of hypertension and cardiac arrhythmia. One of the side effects of the chronic nifedipine treatment is gingival enlargement. The pathomechanism of this side effect is not fully understood. The main objective of the present study was to evaluate the potential role of different factors in the development and severity of gingival hyperplasia. The incidence and severity of gingival enlargement were examined around the six surfaces of... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[The treatment of life-threathening ventricular tachyarrhythmias in coronary artery disease - Antiarrhythmic drug or implantable cardioverter-defibrillator?]

BORBOLA József

[Sudden cardiac death due to sustained ventricular tachyarrhythmias accounts for approximately 50% of all cardiovascular deaths. From the major therapeutic options currently available, antiarrhythmic drug therapy and implantation of automatic car dioverter-defibrillators could be applied to the great majority of patients. Both early observations on automatic implantable cardioverter-defibrillator devices and more recent prospective, randomized, multicenter trials with long-term outcome data... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[Stress adaptation of te myocardium in the presence of systemic disorders]

FERDINANDY Péter

[Effective therapeutic strategies for protecting the ischemic myocardium are much sought after. Ischemic heart disease in humans is a complex disorder often associated with other systemic diseases such as dyslipidemia, hypertension and diabetes mellitus exerting multiple biochemical effects on the myocardium. Ischemic preconditioning of myocardium is a well-described adaptive response where brief exposure to ischemia markedly enhances the ability of the heart to tolerate a subsequent ischemic... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[Ischemic preconditioning of the myocardium; The clinical experience]

SIMON Kornél, SZELIER András

[The authors give an account of the pathomechanism of ischemic preconditioning. This complex adaptation is achieved by the joint compliance of perfusion, metabolism, function and morphology. The process is triggered by repeated ischemic attacks when transmitter substances are liberated during ischemia, as seen in previous experiments. These modulators are the possible substrates of pharmacologic preconditioning. The principle of parallel treatment of perfusion and metabolism is reviewed with... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

Lege Artis Medicinae

SEPTEMBER 01, 2000

[ Gratitude money in Hungarian healthcare; Who, to whom, why, how much?]

NAGY András László

[In the last year, it was brought to life almost at the same time Minister of Health, the so-called Thanksgiving Committee, and began research - commissioned and supported by the Central European University and the State Treasury - by Tárki (Géza Bognár and Róbert Iván Gál, supervisor János Kornai). The studies summarizing the results of the two programs also became known at almost the same time (the report of the Thanksgiving Committee has since been published in book form by Springer... tovább »

Lege Artis Medicinae

SEPTEMBER 01, 2000

[ Healing by Jesus and faith]

SIKET Nándor

[Today’s doctors face a wide variety of challenges. They are expected to be accurate, to do everything regularly and precisely, all of course in such a way that they are never mistaken. Many times we want doctors to reap a final and total victory over death. However, this is still not possible. Why did this happen? What is the reason that today’s doctor is expected to do the impossible?]