Lege Artis Medicinae - 2000;10(04)

Lege Artis Medicinae

APRIL 01, 2000

[THE ROLE OF INFECTIOUS AGENTS IN THE ETIOLOGY AND PATHOGENESIS OF ATHEROSCLEROSIS]

VÁLYI-NAGY István, PETŐ Mónika, CSÁSZÁR Albert, VIRÓK Dezső, BURIÁN Katalin, HELTAI Krisztina, GÖNCZÖL Éva

[The well-known risk factors of atherosclerosis (high level of serum cholesterol, high blood pressure, diabetes, smoking) can only be re cognized in about half of the patients. Athero sclerosis begins in childhood. In vivo and in vitro data suggest that certain pathogens, like the intracellular bacterium Chlamydia pneu moniae (member of the Chlamydia genus) and cytomegalovirus (member of the herpesvirus family) may play a role in the development of atherosclerosis. Both pathogens infect the... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Disparity in the perception of the disease in asthmatics and their pulmonologists plus resource in Hungary (HUNAIR study)]

MAGYAR Pál, GYURKOVITS Kálmán, HERJAVECZ Irén, BÖSZÖRMÉNYI Nagy György

[INTRODUCTION - Bronchial asthma is a chro­nic disease having an increasing prevalence in childhood and adulthood, affecting about 3-5% of the population in the developed countries. The AIR study in the United Kingdom compared the perception of the disease in asthmatic patients' to the view of their physicians (pulmonologists). Based on the results of AIR Study the Hungarian Board of Pulmonologists conducted a partially different survey in Hungary (H UNAIR Study). The fundamental objective... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Modern approach to functional gastrintestinal disorders]

LONOVICS János

[Functional gastrointestinal disorders defined as a variable combination of chronic or recurrent gastrointestinal symptoms not explained by structural or biochemichal abnormalities, are everpresent in the society and in physicians' offices. These conditions account for half of the referrals to gastroenterologists, at least in the ,,developed countries". The pathophysiological mechanisms involved in the pathogenesis of these disorders are complex. The symptoms are believed to be biologically... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Funcitonal Dyspepsia]

SIMON László, LONOVICS János

[Functional dyspepsia is defined as a group of different epigastric symptoms without definite morphological, biochemical or infectious origin, having overlapping clinical features. The pathogenesis of the syndrome is surely multi factorial, involving the alterations of visceral perception, as well. Gastric acid hypersecretion does not play an essential role in the development of symptoms, however its pharmacological inhibition may result in symptomatic improvement. Several clinical studies have... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Irritable bowel syndrome is s representative of functional bowel diseases]

WITTMANN Tibor

[New concept for the irritable bowel syndrome (IBS) has been accepted in the medical practice based on the information obtained in the last two decades about the pathogenesis of the disease. This new pathogenetical concept stimulated the revision of the current pharmacotherapy and the development of new classes of drugs. Several mechanisms are involved in the development of typical symptoms: the role of motility disorders, visceral hypersensitivity and alterations in the peripheral and central... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Diagnosis and management of irritable bowel syndrome]

ÚJSZÁSZY László, TÚRY Ferenc

[The basis for the diagnosis of irritable bowel syndrome is the evaluation of the patient's symptoms. The wide-ranging use of this diagnosis (irritable bowel syndrome, IBS) in the past was equivalent to the exclusion of different organic diseases. Today's use, as a „residual diagnosis" accompanies patients with severe clinical signs, psychiatric comorbidity and older age. Based on the Rome Consensus Criteria I and II, initiating the treatment based on dominant symptoms is an important part of... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[New approaches in the pharmacotherapy of irritable bowel syndrome]

WITTMANN Tibor

[New findings and data obtained in the pathophysiology of IBS had promoting role in the revision of pharmacotherapy of IBS and they were crucial to stimulate the development of new classes of drugs. Symptom-specific treatment is based on three groups of drugs: products modifying the gastrointestinal smooth muscle activity, the visceral hypersensitivity and the central modulatory processes. Only small group of products fulfill the new evaluation criteria.]

Lege Artis Medicinae

APRIL 01, 2000

[Psychological relations and the feasibility of psychoterapy in irritable bowel syndrome]

TÚRY Ferenc, ÚJSZÁSZY László

[The authors overview the recent data on the psychiatric relations of irritable bowel syndrome. The characteristic personality factors (mostly depressive and anxiety traits) must be emphasized as well as comorbidity between certain psychiatric disorders and irritable bowel syndrome, with the role of sexual abuse and stress explained. From the field of psychotherapy, the effectiveness of the cognitive-behavioural methods is analyzed most commonly. Data are available supporting the advantages of... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[ Intracoronary stents]

MANISH M. Gandhi, KEITH D. Dawkins

[Over the past five years, there has been a significant increase in the use of intracoronary stents, which are used during percutaneous transluminal angioplasty (PTCA) as an adjunct to revascularization of angina patients. In 1996, 25,000 PTCA interventions were performed in the UK, using stents in half of the patients (mean 46%, standard deviation 15-99%), a fivefold increase over the 1994 data (based on a personal report by HH. Gray).]

Lege Artis Medicinae

APRIL 01, 2000

[Gratitude money in Hungarian healthcare; Attitudes and opinions]

NAGY András László

[With less and less satisfactory funding for health care, the government is striking growing interest in gratitude money. Almost at the same time, the Minister of Health set up the so-called Thanksgiving Committee and began research - commissioned and supported by the Central European University and the State Treasury - by Tárki. Studies summarizing the results of the two programs also became known at about the same time. In our series, we browse in parallel the Commission report, which... tovább »

Lege Artis Medicinae

APRIL 01, 2000

[Ethical aspects of the autonomy of the medical profession]

KAPOCSI Erzsébet

[The term autonomy - as one of bioethics principle - in the domestic and foreign ethics literature dealing with medicine, it primarily means the autonomy of patients. A significant change in recent decades is that the emphasis has shifted in the doctor-patient relationship, which occupies a central place in the relationship system of medical activity, and the law and ethics have also focused on the principle and autonomy of patients. In addition, a number of processes have taken place that... tovább »