Introduction: Cerebrospinal fluid (CSF) leakage is an abnormal connection between the subarachnoid space and the extracranial space. CSF leak is typically classified as traumatic, iatrogenic or idiopathic. Many CSF leaks heal on their own, but others require complex surgical repair.
Aims and methods: We would like to present the cases diagnosed and operated by our multidisciplinary team between 2018 and March 2024 (excluding malignant tumours, pituitary surgery and craniopharyngeal tumours).
Results: A total of 51 surgeries were performed during this period. CSF leaks were mainly located in the anterior cranial fossa (41/51; 80%). The success rate of primary closure was 92% (47/51). Depending on the size, location and etiology of the CSF fistula, different possible closure modalities were chosen. In all cases of unsuccessful closure at first attempt, reoperation was performed, optionally with the addition of a lumbar drain insertion (2/4; 50%).
Conclusion: The transnasal endoscopic sinus surgery for CSF leakage has high success rate, low morbidity and stable long-term results.
