Lege Artis Medicinae

[LOW GRADE FIBROMYXOID SARCOMA OF THE TEMPORALIS MUSCLE - A CASE REPORT]

KOVÁCS S. Krisztián1, FAN Rong1, MICHALS Edward A.2, DÓSA Sándor1, VILLANO John L.3, VÁLYI-NAGY Tibor1

NOVEMBER 10, 2008

Lege Artis Medicinae - 2008;18(11)

[INTRODUCTION - Low grade fibromyxoid sarcomas (LGFMS) in most cases arise in the skeletal muscle primarily in young to middleaged adults. Males are affected more commonly than females. The tumour tipically arises in the lower extremities, particularly the thigh. Hyalinizing spindle cell tumor with giant rosettes is a variant of LGFMS that demonstrates a significant overlap with classic LGFMS regarding patient age and tumor location, histological appearance and metastatic potential. CASE REPORT - A 76 year-old male presented with a ten-year history of a painless, slowgrowing, hard consistency, left-sided temporal mass. The radiological differential diagnosis included liposarcoma, malignant fibrous histiocytoma and rhabdomyosarcoma. Histopathological examination revealed low grade fibromyxoid sarcoma featuring low cellularity, collagenized areas and alternating myxoid areas, and a focal whorling pattern of tumour cells that were immunoreactive for vimentin, but were negative for S100, CD34, muscle specific actin, desmin and cytokeratin (AE1/AE3). CONCLUSIONS - To the best of our knowledge, this is the first report of low grade fibromyxoid sarcoma involving the temporalis muscle.]

AFFILIATIONS

  1. University of Illinois at Chicago, College of Medicine, Departments of Pathology
  2. University of Illinois at Chicago, College of Medicine, Department of Radiology
  3. University of Illinois at Chicago, College of Medicine, Department of Medicine, Section Hematology and Oncology

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