Lege Artis Medicinae - 2021;31(05-06)

Lege Artis Medicinae

JUNE 07, 2021

[Inflammation and autoimmunity in COVID-19]

SZEKANECZ Zoltán, SZAMOSI Szilvia, SZŰCS Gabriella

[The course of COVID-19 has several stages according to the elapsed time and severity. Cytokine storm-induced multisystemic inflammatory syndrome (MIS) and consequent multiorgan failure occur in severe and critical phases. From a pathological point of view, there is important the co-presenting of inflammation (endothelitis) and microthrombotic events. Beyond respiratory failure, they may harm the cardiovascular and nervous system, the liver and the kidneys. COVID-19 may be associated also with... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[Practical aspects of anticoagulant treatment during the COVID-19 pandemic]

KOMÓCSI András

[Coronavirus infection has a multiple im­pact on the coagulation system and anti­coagulant therapies. Patients admitted with COVID-19 have un­usually high incidence of coagulation ab­normalities. The incidence of atrial fibrillation (AF) seems also to be more frequent among COVID-19 out- and especially in-patients. Among COVID-19 patients receiving oral anticoagulant therapy, for minimizing the risk of bleeding or thromboembolic complications there should also be considered the renal and... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[Lipid lowering therapy during COVID-19 pandemic]

MÁRK László

[The COVID-19 pandemic posed significant challenges to all healthcare systems of the world as created a new situations above the large number of people infected, solutions of which were lacking any previous patterns. Former experiences were specifically needed among physicians who practised usually with therapies supported by evidence based clinical experiences thus they were working along the principles of Evidence-Based Medicine. The new observations and recommendations for treating infected... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[Hypertension, COPD and COVID-19. Focus on antihypertensive therapy]

FARSANG Csaba

[Chronic obstructive pulmonary disease is a very common comorbidity of hypertension and it is often unrecognised by physicians. The factors involved in the pathomechanism of both diseases should be realised when choosing treatment. Among factors, hypoxia, increased tone of sympathetic nervous system and activation of renin-angiotensin-aldosterone system should primarily be considered. Vascular wall damage and endothelial dysfunction has an important role in both conditions. The goals of... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[COVID-19 and Parkinson’s disease]

TÓTH Adrián, TAKÁTS Annamária

[Parkinson’s disease is the elderly people’s condition which increases the risk of infections in the upper airways in its ad­vanced stages. Specific diseases (as hypertension, diabetes mellitus), older age and the male sex are significantly worsening the course of COVID-19. It would be challenging to examine parallel these diseases, since they are raising two important ques­tions. First, if Parkinson’s disease be a risk factor of COVID-19 morbidity and mortality. Se­condly, how the COVID-19... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[Epilepsy in coronavirus pandemic]

SZŰCS Anna, HALÁSZ Péter, NARULA Lalit

[We aim to review the impact of COVID-19 pandemic on epilepsy and epilepsy-care. While the virus has no specific link with epilepsy, it may affect the nervous system both directly and indirectly, leading to seizures in several ways. The hyper-coagulable state occurring with the infection may cause strokes leading to seizures. The infection may first manifest in the form of disturbances of consciousness and behaviour, seizures, and even status epilepticus. The interactions of... tovább »

Lege Artis Medicinae

JUNE 07, 2021

[Potential impact of human genetic variations in COVID-19 infection ]

VÁRNAI Réka, SZENTPÉTERI L. József, SIPEKY Csilla

[The aim of COVID-19 Host Genetics Initiative (HGI) research collaboration is to identify human genetic variation that influences responses to SARS-CoV-2 infection and its subsequent disease, COVID-19. In the COVID-19 HGI consortium more than 1000 scientists share their own data. The authors of this study participate in the Hungarian communication of the published results at the request of COVID-19 HGI.]

Lege Artis Medicinae

JUNE 07, 2021

[Negative pressure wound care while covid-19 pandemic: treatment of necrotizing fasciitis and retroperitoneal abscess]

ZÁDORI Gergely, SUSÁN Zsolt, TÓTH Csaba Zsigmond, TÓTH Dezső, SZENTKERESZTY Zsolt

[Necrotizing fasciitis is a rare and high mortality condition. Most commonly it is spreading in the extremi­ties, abdominal wall soft tissues and perineal region, but occurs rarely in the retroperitoneal space too. Primary treatment is debridement with administered antibiotics, supported by negative pressure wound care. The present case report concerns a successful treatment of an extensive necrotizing fasciitis spreading from the hip region and ending up in a retroperitoneal abscess. A... tovább »