Lege Artis Medicinae - 2012;22(02)

Lege Artis Medicinae

FEBRUARY 20, 2012

[The role of antilipidaemic therapy in chronic kidney disease]

CSÁSZÁR Albert

[In chronic kidney disease (CKD), the risk of cardiovascular mortality is remarkably high, which is partly due to lipid alterations. The results with statin treatment in cardiovascular prevention studies and in CKD, and their metaanalysis show that antilipidaemic therapy decreases overall and cardiovascular mortality in the predialysed state. On the basis of the new study SHARP, coadministration of simvastatin plus ezetimib also significantly reduces the number of atherosclerotic events in... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

[The risk of nonsteroidal antiinflammatory drugs]

FARSANG Csaba

[During the past ten years, a number of original publications, reviews and metaanalyses were published on the cardiovascular (CV) safety of nonsteroidal antiinflammatory drugs (NSAIDs). These data were summarised in several previous publications. As this group of medicines is very frequently used and many of them are available over the counter (OTC), their risks require particular attention. Recently, new analyses have been published on previously discussed preparations as well as on new drugs... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

[Potentials and limitations of the application of RNA interference]

KISS-TÓTH Éva, JUHÁSZNÉ Szalai Adrienn, KOSKA Péter, KISS-TÓTH Emőke, BARKAI László, FODOR Bertalan

[The discovery of RNA interference revolutionised our knowledge about regulation. Small interfering RNA sequences, which have a central role in this phenomenon, go through a complex maturation process. By means of their antisense effect, they result in the degradation of homologuous RNA sequences or transcriptoinal repression in the cell. Due to its advantages, the application of gene silencing has rapidly become prevalent in basic research, especially in the field of molecular biology.... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

[Non-HDL-cholesterol and its significance]

SIMONYI Gábor

[The role of LDL-cholesterol in cardiovascular risk has been established in a number of studies. According to current recommendations, therefore, the primary goal of lipidlowering therapy is reducing the level of LDL-cholesterol. Of lipid-lowering drugs, statins are the most efficient in reducing cardiovascular risk. According to large studies on statins, however, there is a significant residual risk even in patients receiving aggressive treatment. It is well known that many patients continue... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

[Current status of the laboratory diagnosis of tuberculosis in Hungary]

KÖDMÖN Csaba, SZABÓ Nóra, NAGY Erzsébet

[In the past decade, the epidemiological status of tuberculosis has significantly improved in Hungary. The incidence is today lower than 20 per 100 000 inhabitant, therefore, the laboratory network performing diagnosis needs to look for new challenges. As the yearly number of cases decreases, less examinations will be needed, but a greater emphasis should be placed on shortening the time needed for diagnosis, more efficient culturing, resistance tests and molecular typing performed for... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

[The diagnostic value of a glass of soda water in case of a cardiac space-occupying lesion]

PÁLINKÁS Attila, CZAKÓ László, CSÁSZÁR Ildikó, NAGY Edit, SZABÓ Marianna

[INTRODUCTION - Large hiatal hernias may result in cardiac space-occupying lesions. Our case study discusses the clinical aspects and the possible diagnostic approaches for such large hiatal hernias that cause cardiac compression. CASE REPORT - In an elderly patient with no cardiovascular symptoms, transthoracic echocardiography revealed a left atrial space-occupying mass. The diagnosis regarding the origin of the cardial mass was clarified by a glass of soda water drunk by the patient during... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012

Lege Artis Medicinae

FEBRUARY 20, 2012

[Written and pictorial content in magazines and their possible relationship to eating disorders]

SZABÓ Kornélia, TÚRY Ferenc

[In the current study we reviewed the literature on studies exploring the magazine reading frequency, written and pictorial contents appearing in magazines and their connection to eating disorders. Reading different fashion and fitness magazines has effect on readers through several indirect and direct factors and through trustable and false information. They affect readers' body satisfaction, self-esteem, eating habits and more generally their health behavior. Different theories have been... tovább »

Lege Artis Medicinae

FEBRUARY 20, 2012