Lege Artis Medicinae

[Current status of the laboratory diagnosis of tuberculosis in Hungary]

KÖDMÖN Csaba, SZABÓ Nóra, NAGY Erzsébet

FEBRUARY 20, 2012

Lege Artis Medicinae - 2012;22(02)

[In the past decade, the epidemiological status of tuberculosis has significantly improved in Hungary. The incidence is today lower than 20 per 100 000 inhabitant, therefore, the laboratory network performing diagnosis needs to look for new challenges. As the yearly number of cases decreases, less examinations will be needed, but a greater emphasis should be placed on shortening the time needed for diagnosis, more efficient culturing, resistance tests and molecular typing performed for epidemiological purposes. Our aim is to provide an overview of the status of the diagnostic network of tuberculosis in Hungary and the future challenges it faces, on the basis of data published by the National Korányi Institute of TBC and Pulmonology and the European Centre for Disease Prevention and Control.]

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Lege Artis Medicinae

[Non-HDL-cholesterol and its significance]

SIMONYI Gábor

[The role of LDL-cholesterol in cardiovascular risk has been established in a number of studies. According to current recommendations, therefore, the primary goal of lipidlowering therapy is reducing the level of LDL-cholesterol. Of lipid-lowering drugs, statins are the most efficient in reducing cardiovascular risk. According to large studies on statins, however, there is a significant residual risk even in patients receiving aggressive treatment. It is well known that many patients continue to have dyslipidaemia despite statin therapy, and not all patients with cardiovascular disease have elevated LDL-cholesterol levels. These observations indicate that lipids other than LDL-cholesterol also have a role in the development of atherosclerosis. A growing attention is paid to non-HDL-cholesterol as a cardiovascular risk factor. Calculating non-HDL-cholesterol target is easy: LDL-cholesterol measurement plus 0,8. Non-HDL-cholesterol incorporates a number of atherogenic lipoprotein particles [VLDL-cholesterol, IDL-cholesterol, LDL-cholesterol, and lipoprotein(a)]. As the atherogenic effect of apoB-containing lipoproteins (LDL, IDL-C és VLDL) is significant, they may be stronger predictors of coronary heart disease (CHD) risk than LDL-cholesterol is. Considering the strong correlation between apoB and non-HDLcholesterol and the limitations of apoB measurement (standardisation, cost), non- HDL-cholesterol is a more useful parameter and therapeutic target, especially if triglyceride levels are greater than 2.26 mmol/l.]

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[His Vengeful Heart was Struck by a Bullet – Variations for a Duel on Pushkin’s Anniversary ]

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[Association of diabetes mellitus and peritoneal dialysis]

MÁCSAI Emília, TÖLGYESI Katalin, BENKE Attila

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[Psychedelics and Quasi-Mystical Experiences – Part II ]

SZUMMER Csaba

Lege Artis Medicinae

[Written and pictorial content in magazines and their possible relationship to eating disorders]

SZABÓ Kornélia, TÚRY Ferenc

[In the current study we reviewed the literature on studies exploring the magazine reading frequency, written and pictorial contents appearing in magazines and their connection to eating disorders. Reading different fashion and fitness magazines has effect on readers through several indirect and direct factors and through trustable and false information. They affect readers' body satisfaction, self-esteem, eating habits and more generally their health behavior. Different theories have been explained to account for these associations and several other studies examined empirically the connection between the frequency of magazine reading and eating disorders, as well as the symptoms leading to eating disorders. METHODS - We analyzed and summarized articles between 1975 and 2009 from online databases. We used the following sources: Science Direct (http://www.sciencedirect. com/), Springer-Verlag GmbH (http://www.springerlink.com/) and SAGE Publications Ltd (http://online.sagepub. com/). RESULTS - The pictorial and written magazine contents were associated with the development and maintenance of eating disorders or with symptoms that might lead to eating disorders. The publications comparing to previous years found elevated number of unhealthy food advertisements, unhealthy and radical diet plans and exercise programs. Furthermore the magazines contained conflicting messages about nutrition, body functions and eating disorders. CONCLUSION - Written and pictorial magazine contents, messages might increase the risk for development of eating disorders, especially in vulnerable individuals.]

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Hungarian Radiology

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Lege Artis Medicinae

[Surveillance-examination in the department of internal medicine of a frequented hospital]

SCHAREK Petra, LÉTAY Erzsébet, KATONA Katalin, RÓKUSZ László

[OBJECTIVES - In November 2010, wescreened patients admitted to the MilitaryHospital, 1st Department of Internal Medi-cine for meticillin-resistant Staphylococcusaureusand Gram-negative, extended spec-trum beta-lactamase producing bacteria.We detected the prevalence of colonisationor infection by these strains during hospitalstay. METHODS - We compiled a datasheet toregister patient data and results. Swabsfrom one of the anterior nares, the throatand the rectal area were taken at admissionand discharge after informed consent of thepatients. Microbiological samples wereprocessed by current microbiology guide-lines. RESULTS - During the one-month studyperiod, 134 adult patients were admitted,105 of who consented to the examination.At admission, six patients (5.7%) carriedmeticillin-resistant Staphylococcus aureusand five patients (4.76%) carried extendedspectrum β-lactamase producing Esche-richia coli. In one patient (0.95%) nosoco-mial extended spectrum β-lactamase pro-ducing Enterobacter cloacaewas identifiedin the rectal sample. In two patients (1.9%),rectal colonisation by Streptococcus pyogeneswas detected. CONCLUSIONS - Screening patients formeticillin-resistant Staphylococcus aureusin our department is important because ofthe high rate of patients returning to thehaematologic department, and consideringthat 4.5% of patients admitted to ourDepartment were transported to surgicaldepartments in 2010. It is particularlyimportant to determine the sampling location. The prevalence of rectal colonisatonby extended spectrum β-lactamase produc-ing bacteria was in accordance with international data. We didn’t detect infectionprovoked by the examined bacteria duringthe study period.]

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