Lege Artis Medicinae - 2006;16(12)

Lege Artis Medicinae

DECEMBER 16, 2006

Lege Artis Medicinae

DECEMBER 16, 2006

[THE ROLE OF THE ENDOCANNABINOID SYSTEM]

JÁRAI Zoltán

[Cannabinoid research in the last two decades became one of the most important fields in medical science, mainly because of the discovery of the endocannabinoid system and the understanding of the close connections between this system and several important diseases and pathological states. The endocannabinoid system has been shown to be present and active in many tissues and organs including the central nervous, gastrointestinal and reproductive systems, liver, lungs and bones. Its role in eye... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[CLINICAL ASPECTS OF NOCTURNAL GASTRO-OESOPHAGEAL REFLUX]

DEMETER Pál

[Gastro-oesophageal reflux that occur at night has special clinical features and thus require extra attention. During sleep most anti-reflux mechanisms diminish, which results in prolonged contact between gastric acid and oesophageal mucosa compared to reflux during the day. Nighttime reflux symptoms adversely affect quality of life, vitality, physical and mental health. A further important consequence is the potential exacerbation of respiratory disorders such as asthma and sleep apnea. There... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[SEVERE THERAPY RESISTANT BRONCHIAL ASTHMA]

HERJAVECZ Irén, BÁNKÚTI Beáta, CSOMA Zsuzsanna

[While severe asthma associated with high morbidity affects a relatively small proportion of all patients with asthma, it requires special attention and innovative treatment approaches. Although asthma is by definition characterized by reversible airflow obstruction, the obstruction becomes fixed to some extent and refractory to corticosteroids with the progression of the disease. The underlying change in this phenotype is airway wall remodelling. In allergic asthmatic patients who remain... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[TREATMENT OF HYPERTENSION - RECOMMENDATIONS FOR THE PRACTICE]

PÁLL Dénes

[Hypertension is one of the most common diseases with a prevalence of over 25%. Despite of the availability of modern therapeutic options, the proportion of well-controlled patients is low. Before starting the treatment of patients with hypertension, it is essential to assess cardiovascular risk factors, co-morbidities and damages to target organs, in addition to repeated blood pressure measurements. The author first reviews the non-pharmacological treatment options of hypertension, then... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[NEBIVOLOL FOR THE TREATMENT OF HYPERTENSION AND CARDIAC FAILURE]

JERMENDY György

[Beta-receptor blocking agents are considered a well defined class of drugs for treating hypertension and heart failure. Nebivolol, a thirdgeneration beta-blocker that combines marked beta-1-receptor selectivity with a vasodilator and antioxidant effect, has relatively recently become available in Hungary. The vasodilator effect of nebivolol has proved to be mediated by the endothelial NO pathway. Due to its neutral metabolic effect, nebivolol can safely be used in patients with glucose... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[EFFECTS OF VITAMIN D AND THE EFFICACY OF VARIOUS VITAMIN D PRODUCTS]

BORS Katalin

[An increasing number of studies suggests that the effects of vitamin D is not limited to the regulation of calcium homeostasis, but it is also involved in several other physiologic processes. Vitamin D receptors are present on the surface and in the nucleus of most cells. Vitamin D as a steroid hormone has genomic and non-genomic effects. Vitamin D deficiency is an important problem worldwide, and so is in Hungary. Vitamin D promotes bone formation and mineralization and decreases the rate of... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

[DISCREPANCIES BETWEEN THE CLINICAL AND PATHOLOGICAL DIAGNOSES IN CASES OF MALIGNANT TUMOUR]

KOVÁCS Attila, ILLYÉS György, SCHÖNFELD Tibor, SCHAFF Zsuzsa

[INTRODUCTION - In Hungary, like in other countries, previously undiagnosed diseases are frequently discovered at autopsies despite the availability of modern diagnostic tools. The aim of this study was to determine the accuracy of clinical diagnosis in malignant tumour cases. METHODS - Between 1996 and 2006, 5005 autopsies were performed in our institute. Malignant tumour cases with differing clinical and pathological diagnoses were selected and revised with regard to the localization of the... tovább »

Lege Artis Medicinae

DECEMBER 16, 2006

Lege Artis Medicinae

DECEMBER 16, 2006

[Winter (beta test)]

NÉMETH István

[Beta Civil realism culminated Rated XVII. century Dutch painting, one of the most striking features of secular themes and motifs dominated everyday. Although in some cases also made sure the various biblical, mythological or allegorical representations being.]

Lege Artis Medicinae

DECEMBER 16, 2006