Hypertension and nephrology - 2022;26(01)

Hypertension and nephrology

FEBRUARY 26, 2022

[Dialysis service in coronavirus pandemic]

SZEGEDI János, HORN Péter, GERGELY László, TÖLGYESI Katalin, MOLNÁR Gergely

[The coronavirus pandemic started at December 2019 from Wuhan. The rate of spread of the coronavirus epidemic has shocked the entire world, and the WHO declared it as a pandemic in March 2020. The first case in Hungary was confirmed in March 2020. The infection primarily damages the lungs but can also infect other organs. The relationship between coronavirus infection and the kidney is bidirectional. On the one hand, the infection can cause acute renal damage, and on the other hand, chronic... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[Dialyzed patients with Covid-19 infection in Hungary in 2020]

KULCSÁR Imre

[We have observed the number and mortality of dialyzed patients with Covid-19 infection in 2020 in Hungary. We have summarized all of 54 dialysis facility where adult patients were treated. During the year, 1242 cases of infection were confirmed in patients undergoing dialysis. 16% (753/4704) of incident dialysis patients were infected. The number of dialysis patients with all Covid-19 infections was 1995. 31.1% of infected patients have died. The mortality was higher in large hemodialysis... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[Metabolic effects of cardiovascular drugs]

FÜLÖP Tibor

[Cardiovascular drugs are used for the treatment and primary and secondary prevention of diseases affecting the cardiovascular system. Like all drugs, these drugs may have pharmacological effects in addition to their therapeutic effects. Of particular importance are the effects that affect, have a positive or negative effect on global or cardiac metabolism. In addition to primary cardiovascular diseases, most cardiovascular diseases are strongly influenced by patient’s metabolic status and... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[Lupus nephritis, 2022]

CZIROK Szabina, DOLGOS Szilveszter

[The lupus nephritis (LN) is one of the most frequent manifestation of SLE which causes higher morbiditiy and mortalitiy of the patients if it appears. Although the use of glucocorticoides, cyclophosphamide and mycofenolat mofetil and the protection of the kidney with conservative therapy has significantly improved the outcome of the disease, but the long-term renal outcome and risk of death from LN have not changes over the last 20 years. Furthermore, the side effect of our medications used as... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[The safety and efficacy of LCP-tacrolimus in maintenance immunosuppressive therapy after kidney transplantation]

CSEPREKÁL Orsolya, KEGLEVICH András, REMPORT Ádám

[This paper provides a comprehensive review of a new, innovative formulation of one of the cornerstones of immunosuppressive maintenance therapy, tacrolimus (LifeCycle Pharma Tac, LCP-Tac, LCPT). This brief overview provides a deeper insight into the scientific literature of LCP-Tac. In summary, once daily LCP-Tac, a medication available in routine clinical practice, can provide effective and safe blood levels in renal transplant patients. Furthermore LCP-Tac may require lower doses of... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[Beyond the blood sugar reduction. SGLT-2 inhibitors in kidney protection]

SIMONYI Gábor

[Results of cardiovascular safety studies with SGLT-2 inhibitors have shown that in addition to their hypoglycaemic and beneficial cardiovascular effects, they are renoprotective. A number of mechanisms underlying the renoprotective effects of SGLT-2 inhibitors have been shown to reduce albuminuria and deterioration of renal function. Their nephroprotective effects extend over a very wide range of eGFR and albuminuria categories. In the DAPA-CKD study, dapagliflozin was shown to exert its... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[Telmisartan plus amlodipine single-pill combination therapy to achieve blood pressure goal values in hypertensive patients treated by general practitioners – an observational study]

ÁMON Tamás, BARACSI-BOTOS Viktória, MÉSZÁROS Ágota, JÁRAI Zoltán

[Background: Current European guidelines on the management of hypertension suggests a simple and easily applicable therapeutic strategy to increase effectiveness. Important component of this strategy is the application of single-pill combination (SPC) of RAS inhibitor in combination with calcium antagonists or diuretics as a first step. Primary objective: To assess the percentage of patients reached goal blood pressure ranges after 12 weeks of fix dose combination therapy with telmisartan plus... tovább »

Hypertension and nephrology

FEBRUARY 26, 2022

[SARS-CoV-2 fertőzés során kialakult alsó végtagi akut artériás elzáródás esete. „Örülök, hogy élek…”]

VIRÁG Éva, JACZÓ Zsuzsana, VÁRADI Tímea, RAPCSÁNYI Andrea, SZABÓ Ildikó, RADELECZKI Sándor, GASPARICS Roland, SIMONYI Gábor, BARANYAI Árpád, SKRIBEK Levente, NAGYSZEGI Dóra, FARKAS Katalin, KOLOSSVÁRY Endre