Hypertension and nephrology - 2012;16(03-04)

Hypertension and nephrology

SEPTEMBER 21, 2012

[Hypertensive and cardiovascular risks of nonsteroidal antiinflammatory drugs]

FARSANG Csaba, BEDROS J. Róbert, ALFÖLDI Sándor

[Nonsteroidal antiinflammatory drugs (NSAIDs) are among the most frequently used medicines. During the last ten years several original publications, reviews and meta-analyses were published on the cardiovascular safety of NSAIDs and the results underlined their potentially harmful cardiovascular side effects. It can also be emphasized that there are substantial differences between different compounds, and the CV risk does not depend on the ratio of COX-1/COX-2 selectivity. Cardiovascular risk... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[The apparatus which controls our kidney too. - Part 1]

ROSIVALL László

[The series gives a brief overview on the discovery of the juxtaglomerular apparatus (JGA), an interesting story, as well as on details of its structure and function down to the molecular level. The discovery of JGA, i.e., a phylogenetically ancient organ, is a fine example of the close morphological and functional correlations characteristic of living organisms. Presented are the JGA related misconcepts and the underlying theoretical and practical difficulties. Utilization of the most modern... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Etiology and diagnosis of renal failure after pediatric cardiac surgery]

TÓTH Roland, CSERÉP Zsuzsanna, SZÉKELY Andrea

[Acute kidney injury is a common and severe clinical problem in children after cardiac surgery, defined by abrupt decline in renal function, with manifestations ranging from minimal elevation of serum creatinine to anuric renal failure. The condition can have a negative influence on the long-term outcome of the illness. The problem is more likely in pediatric cardiac surgery, where the low birth-weight neonates and premature infants can be even more affected. On the other hand chronic renal... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Is there a role of triple combination in the therapy of hypertension? - Antihypertensive efficiency of perindopril-amlodipine-indapamide]

PÁLL Dénes, SZÁNTÓ Ildikó, PARAGH György, KATONA Éva

[Blood pressure reduction to target level decreases cardiovascular morbidity and mortality. However, in the vast majority of cases, this can be achieved only with a (multiple) combination regimen. The primary objective of the PAINT (Perindopril- Amlodipine plus Indapamide Combination for Controlled Hypertension Non-intervention Trial) study was to evaluate the efficacy of combination therapy with perindopril, amlodipine, and indapamide in patients who had not reached target blood pressure with... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Estimation of serum uric acid in the Hungarian population]

KÉKES Ede, BARNA István, DAIKI Tenno, DANKOVICS Gergely, KISS István

[The clinical significance of serum uric acid markedly increased in the last years, especially in the civilized countries, but the abnormal serum uric acid level shows a significantly strong increasing tendency worldwide. The high level of uric acid is an integral part of metabolic syndrome. Today we recognized the important role of xanthine oxidase in the clinical practice for developing of oxidative stress in some tissues and organs. In 2011 during the Hungarian Health Care Screening Program... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[The prognostic role of serum albumin levels in survival of chronically hemodialized patients]

KULCSÁR Imre, SZAKÁCS Gyuláné, SZEGEDI János, KISS István

[The authors have investigated the survival of 238 patients on chronic haemodialysis program regarding serum albumin levels (measured at starting dialysis and at the end of observation) adjusted for age, gender, diabetes, serum haemoglobin and body weight. The mean observational period was 5.5 years. Our investigation has documented a tight positive correlation between the survival and serum albumin levels both at starting and ending of investigation independently of epidemiological parameters.... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Prevalence of bone abnormalities and soft tissue calcification and their determining factors in dialyzed patients]

KISS Zoltán, AMBRUS Csaba, SZABÓ András, SZEGEDI János, BALLA József, TÖRÖK Marietta, LADÁNYI Erzsébet, CSIKY Botond, ÁRKOSSY Ottó, TÚRI Sándor, KULCSÁR Imre, KISS István

[Disturbances of bone and mineral metabolism are frequent complications of chronic kidney disease. In the last decades, increasing evidence of both pathophysiological and epidemiological nature support the relationship between bone disease and soft tissue calcification. In this current research, we analysed characteristics, determining factors and relationship of these two complications in a nationwide, cross-sectional cohort of dialysed patients. We collected demographical data (age, gender,... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Effect of bilateral catheter-based renal artery sympathetic denervation on blood pressure, therapy and baroreflex-sensitivity in a patient with resistant hypertension]

LÉGRÁDY Péter, NAGY Ferenc Tamás, THURY Attila, BAJCSI Dóra, FEJES Imola, SIMON Judit, NAGY Endre, UNGI Imre, ÁBRAHÁM György

[Hypertension is a global problem all over the world and also in Hungary. Although there is a wild spectrum of pharmacological and non-pharmacological antihypertensive interventions, the rate of hypertensive patients not achieving the goal blood pressure is still high. Recently developed endovascular catheterbased technology enables selective radiofrequent denervation of kidney through the lumen of renal artery. We report a case of a 52-year old hypertensive women on a combination of 11... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

[Protein-energy wasting and quality of life in kidney transplant recipients]

UJSZÁSZI Ákos, VÁRADY Tímea, CZIRA Mária Eszter, FORNÁDI Katalin, NOVÁK Márta, MUCSI István, MOLNÁR Miklós Zsolt

[Chronic kidney disease has profound effects on the health related quality of life (HRQoL) of patients with serious physiological, psychological and socio-economic implications. The co-occurrence of protein-energy wasting (PEW) and inflammation in end stage renal disease patients is associated with worse HRQoL and increased mortality. We designed this study to examine the relationship between nutritional and inflammatory status and HRQoL in kidney transplant recipients. Data from 100 randomly... tovább »

Hypertension and nephrology

SEPTEMBER 21, 2012

Hypertension and nephrology

SEPTEMBER 21, 2012

[Professor István Taraba MD., the scientist, physician and man. - „Difficulties are to defeat them!”]

POLNER Kálmán

[Only few such outstanding physicians lived, whose achievements and personality influenced the development of the Hungarian nephrology as remarkably as professor István Taraba did. He started his university career as an experimental researcher at the Institute of Physiology on Semmelweis University, Budapest, then at the age of 34, after completing his Ph.D thesis, decided to treat patients to utilize his acquired knowledge in the field of renal failure’s pathophysiology. This way he devoted... tovább »