Hungarian Radiology

[XII. Congress of the Hungarian Radiographers]


OCTOBER 20, 2007

Hungarian Radiology - 2007;81(05-06)



Further articles in this publication

Hungarian Radiology

[XV. Symposium and Postgradual Training of the Pediatric Radiologists]


Hungarian Radiology

[Prenatal detection of campomelic dysplasia by sonography]


[INTRODUCTION - The campomelic dysplasia is a disorder characterized by short and bowed lower limbs resulting in dwarfism. CASE REPORT - In the case of a 21-year-old primipara woman the second screening ultrasonography raised the suspicion of short and bowed lower limbs of the fetus, at the 19th week of the pregnancy. Repeated examinations proved the presence of short and bowed femurs and tibias and abnormal echogenecity of the bones. The upper limbs were almost normal in length. During the 19th week of pregnancy, after a genetic analysis in agreement of the parents the pregnancy was interrupted without any complication. Photography and Xray of the fetus confirmed the diagnosis. CONCLUSION - Fetal ultrasonography should include exact size measurement and observation of the shape of the long bones, making possible the early detection of limb anomalies. The anomaly being proven by positive genetic analysis the pregnancy can be interrupted at the parents' request.]

Hungarian Radiology

[Technical aspects of MR urography based on two cases]

HORVÁTH László, BOGNER Péter, NAGY Gyöngyi, BAJZIK Gábor, VANDULEK Csaba, REPA Imre

[Intravenous urography has been the gold standard in diagnostic radiology studying the urogeintal system. However, ultrasound and other cross-sectional imaging methods have brought major change in this area. Beside modern (multislice) CT examinations the methods of MR urography are more frequently applied making possible both static and dynamic examinations beyond the wellknown advantages of MR imaging. The authors describe two complemetary methods of MR urography which provide a complete evaluation of the urinary system. The first method is aimed to image stationary fluid by using heavily T2 weighted turbo spin echo pulse sequences. This measurement well depicts the dilations of the excretory system even with little or no excretion of urine. The second method is analogous with the traditional IVU, as the excretion of a less nephrotoxic gadolinium based contrast medium followed by a T1 weighted gradient echo pulse sequence (possibly dynamic) helps to visualise the renal cavities and the urinary pathways. Normal renal function is a prerequisite when using this technique in order to visualise normal and obstructed urinary pathway disorders. The use of MR urography together with traditional MR methods may significantly reduce the number of invasive examinations and methods based on X-ray radiation exposure. MR urography may be exceptionally important in the uroradiological study of distensions of renal cavities in pediatric cases, pregnant women and renal transplant patients or in case of contrast material allergy.]

Hungarian Radiology

[Jugulotympanic glomus tumor - 7-year follow up of a rare disease]


[INTRODUCTION - The jugulotympanic glomus tumor is rare pathology with slow progression and its treatment is difficult. We present the imaging and clinical findings of a case obtained during 7 year follow up period. CASE REPORT - A 77-year-old female patient was admitted in 2000 with slowly progressing swelling of the neck. A palpable soft, non-painful resistance was noted at the main neck vessel region. Angiography revealed a jugulo-tympanic glomus tumor and embolization of the feeders from the external carotid artery was also performed. The size of the tumor is decreased but a clinically silent floating thrombus appeared in the internal jugular vein. It was treated with LMWH. Three years later external carotid artery transsection and denudation was performed. Slow progression of the tumor toward the subclavian vein was detected without intracranial invasion, in 2004. Repeated angiography was performed in 2005, but embolization was not possible due to technical reasons. Irradiation was considered to diminsh clinical symptoms, however due to the old age of the patients and the risk of bleeding, the treatment was not performed. Symptomatic therapy has been applied. CONCLUSION - Jugulo-tympanic glomus tumor is one of the non-chromaffin paragangliomas. The clinical symptomps are dominated by the paresis of IX.-X.-XI. nerves. Semimalignant disease and metastases are rare. The course is mostly influenced by compression syndromes and intracranial spread. The therapy is mostly microsurgical but preoperative embolization is frequently done to decrease blood loss. Surgical therapy is recommended with prior embolization of the feeders in order to decrease the blood supply of the mass. If surgery cannot be carried out irradiation therapy is needed. Unfortunately, all of these procedures are seldom curatives because of natural course of the disorder and the high frequency of recurrencies.]

Hungarian Radiology

[Professor Mózes Péter was awarded professor emeritus title]


All articles in the issue

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Clinical Neuroscience

[Advanced Parkinson’s disease characteristics in clinical practice: Results from the OBSERVE-PD study and sub-analysis of the Hungarian data]

TAKÁTS Annamária, ASCHERMANN Zsuzsanna, VÉCSEI László, KLIVÉNYI Péter, DÉZSI Lívia, ZÁDORI Dénes, VALIKOVICS Attila, VARANNAI Lajos, ONUK Koray, KINCZEL Beatrix, KOVÁCS Norbert

[The majority of patients with advanced Parkinson’s disease are treated at specialized movement disorder centers. Currently, there is no clear consensus on how to define the stages of Parkinson’s disease; the proportion of Parkinson’s patients with advanced Parkinson’s disease, the referral process, and the clinical features used to characterize advanced Parkinson’s disease are not well delineated. The primary objective of this observational study was to evaluate the proportion of Parkinson’s patients identified as advanced patients according to physician’s judgment in all participating movement disorder centers across the study. Here we evaluate the Hungarian subset of the participating patients. The study was conducted in a cross-sectional, non-interventional, multi-country, multi-center format in 18 countries. Data were collected during a single patient visit. Current Parkinson’s disease status was assessed with Unified Parkinson’s Disease Rating Scale (UPDRS) parts II, III, IV, and V (modified Hoehn and Yahr staging). Non-motor symptoms were assessed using the PD Non-motor Symptoms Scale (NMSS); quality of life was assessed with the PD 8-item Quality-of-Life Questionnaire (PDQ-8). Parkinson’s disease was classified as advanced versus non-advanced based on physician assessment and on questions developed by the Delphi method. Overall, 2627 patients with Parkinson’s disease from 126 sites were documented. In Hungary, 100 patients with Parkinson’s disease were documented in four movement disorder centers, and, according to the physician assessment, 50% of these patients had advanced Parkinson’s disease. Their mean scores showed significantly higher impairment in those with, versus without advanced Parkinson’s disease: UPDRS II (14.1 vs. 9.2), UPDRS IV Q32 (1.1 vs. 0.0) and Q39 (1.1 vs. 0.5), UPDRS V (2.8 vs. 2.0) and PDQ-8 (29.1 vs. 18.9). Physicians in Hungarian movement disorder centers assessed that half of the Parkinson’s patients had advanced disease, with worse motor and non-motor symptom severity and worse QoL than those without advanced Parkinson’s disease. Despite being classified as eligible for invasive/device-aided treatment, that treatment had not been initiated in 25% of these patients.]

Clinical Oncology

[Complications of infusion treatment with emphasis on extravasation of cytostatics]

HARISI Revekka

[The extravasation of cytostatics is the most signifi cant complication of infusion therapy in cancer treatment. Extravasation refers to the inadvertent infi ltration of cytostatic drugs into subcutaneous or subdermal tissues surrounding the intravenous or intraarterial administration site. According to literature data incidence estimates between 0,01-7%. Extravasated drugs are classifi ed according to their potential for causing damage as vesicant, irritant and nonvesicant. Knowledge of risk factors, the patientrelated and treatment-related ones is important to minimize the occurrence of extravasation. In order to reduce the risk of extravasation, the staff involved in the tumor infusion therapy must be specially trained to implement several preventive and therapeutical protocols. In 2012, ESMO-EONS has put together a new comprehensive treatment protocol on the topic of cytostatics extravasation. Protocol recommended that every oncological department, who administers chemotherapy have to have extravasation trained team and a standby extravasation kit. According to the new ESMO-EONS guideline subcutaneous corticoids are not recommended, anymore. In case of mechloretamine extravasation the recommendation is immediate subcutaneous injection of sodium thiosulfate. After extravasation of anthracyclines, mitomycin C and platin salts the best treatment opportunity is subcutan dimethyl sulfoxide administration. In case of anthracyclines’ extravasation intravenous dexrazoxane treatment is also effective. Hyaluronidase, injected into or under the skin, facilitates absorption of extravasated drugs because of increases connective tissue permeability, promotes the spreading and reduces the local concentration of the extravasated citostatic agents. Hyaluronidase might be effi cacious in preventing skin necrosis by extravasation due to vinca alkaloids. The treatment of unresolved tissue necrosis or pain lasting more than 10 days is surgical debridement. Because of the medical and juristic importance of the extravasation event, it is necessary to establish uniform guidelines for treatment of extravasation, in all Hungarian Oncological Centers.]

Clinical Neuroscience

[Decisional collisions between evidence and experience based medicine in care of people with epilepsy]


[Background – Based on the literature and his long-term clinical practice the author stresses the main collisions of evidence and experience based medicine in the care of people with epilepsy. Purpose – To see, what are the professional decisions of high responsibility in the epilepsy-care, in whose the relevant clinical research is still lacking or does not give a satisfactory basis. Methods – Following the structure of the Hungarian Guideline the author points the critical situations and decisions. He explains also the causes of the dilemmas: the lack or uncertainty of evidences or the difficulty of scientific investigation of the situation. Results – There are some priorities of experience based medicine in the following areas: definition of epilepsy, classification of seizures, etiology – including genetic background –, role of precipitating and provoking factors. These are able to influence the complex diagnosis. In the pharmacotherapy the choice of the first drug and the optimal algorithm as well as the tasks during the care are also depends on personal experiences sometimes contradictory to the official recommendations. Same can occur in the choice of the non-pharmacological treatments and rehabilitation. Discussion and conclusion – Personal professional experiences (and interests of patients) must be obligatory accessories of evidence based attitude, but for achieving the optimal results, in some situations they replace the official recommendations. Therefore it is very important that the problematic patients do meet experts having necessary experiences and also professional responsibility to help in these decisions. ]

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[New nursing tasks in the Children’s Heart Centre]

VINCZE Beatrix

[The Children’s Heart Centre began operation in the Gottsegen György Hungarian Institute of Cardiology in 1999. In response to the technical advancements of the recent period and the achievements of medical science, paramedical workers are faced with new tasks such as the care of children undergoing interventional cardiology, ablative intervention and treatment as a part of the heart transplant program. The nurses and assistants assimilate the skills set necessary for performing the new tasks through in-house education programs and further training courses. An important challenge for nursing management is incorporating the changes into the operating procedures of the departments, and ensuring the human resources necessary to provide the care. The author’s aim is to give an insight into these specialist nursing tasks. ]

Lege Artis Medicinae

[Echocardiographic data in Hungarian top-level water polo players]

PAVLIK Gábor, KEMÉNY Dénes, KNEFFEL Zsuzsanna, PETREKANITS Máté, HORVÁTH Patrícia, SIDÓ Zoltán