Clinical Oncology

[ESMO Clinical Research Observatory (ECRO). Improving the effi ciency of clinical research through rationalisation of bureaucracy]

PEREZ-GRACIA Luis Jose1, AWADA Ahmad2, CALVO Emiliano3, AMARAL Teresa4, ARKENAU Hendrik-Tobias5, VIKTOR Gruenwald, BODOKY Gyorgy6, LOLKEMA P Martijn7, NICOLA Di Massimo8, PENEL Nicolas9, VERA Ruth10, SANMAMED F Miguel1, DOUILLARD Jean-Yves11

AUGUST 28, 2020

Clinical Oncology - 2020;7(3)

AFFILIATIONS

  1. Department of Oncology, University Clinic of Navarra and Health Research Institute of Navarra (IdiSNA), Pamplona, Spain
  2. Department of Oncology Medicine, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium
  3. START Madrid-CIOCC, Centro Integral Oncológico Clara Campal, Hospital Universitario HM Sanchinarro, Madrid, Spain
  4. Interdisciplinary Skin Cancer Center, University Medical Center, Tuebingen, Germany
  5. Sarah Cannon Research Institute and University College, London, United Kingdom
  6. Department of Oncology, St László Teaching Hospital, Budapest, Hungary
  7. Department of Medical Oncology, Erasmus Medical Center Cancer Center. Erasmus Medical Center, Rotterdam, The Netherlands
  8. Immunotherapy and Innovative Therapeutic Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
  9. Department of Medical Oncology, Centre Oscar Lambret and Lille University, Lille, France
  10. Department of Medical Oncology, Complejo Hospitalario de Navarra and Navarra Institute for Health Research (IdiSNA), Pamplona, Spain
  11. Scientifi c and Medical Division, European Society for Medical Oncology (ESMO), Lugano, Switzerland

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[Treatment of head and neck squamous cell carcinomas (HNSCC) is exceptionally complex, requiring the close cooperation of the head and neck surgeon, radiation oncologist and medical oncologist. Excellent tumor control should be our primary goal, however, the selection of treatment should not only be guided by oncologic radicality but by the need of satisfactory quality of life (as most local therapies affect respiratory, swallowing and/or speech function), too. Based on the appropriate diagnostic workup, these cancers are classifi ed into early, locoregionally advanced or recurrent/metastatic stages. Each category requires different treatment modalities, further complicated by the localization of the primary tumor and its metastases, performance status of the patient, comorbidities, and the biology of the lesion. In the present review, the authors summarize the basics of the therapy of head and neck cancers.]

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