Clinical Neuroscience

[Infancy meningioma]

GÁTAI György1

DECEMBER 22, 1952

Clinical Neuroscience - 1952;5(04)

[An unusually large, clinically asymptomatic suprasellar meningioma in a three-year-old boy. One of the youngest meningiomas reported to date. Case presentation and lessons learned: importance of early radical surgery, increased ventriculography in childhood.]


  1. Budapesti Orvostudományi Egyetem Elme- és Idegkórtani Klinkája Idegsebészeti Intézet



Further articles in this publication

Clinical Neuroscience

[An interesting case of schizophrenic neologism]


[We describe a rare case of schizophrenic neologism, where the patient produces larger units of speech that he or she has formed. The neologism is a degradation phenomenon and its development is reminiscent of, but qualitatively different from, infantile and dreaming language. Neologistically formed language is called artificial language. We can distinguish between "intelligible" and "non-intelligible" artificial language. In some cases described in the literature, the artificial language has developed on the ground of pathological religiosity. We will attempt to give a pathogenetic explanation of the neologisms observed in these cases. A closer examination of the regularity of the Pavlovian second signalling system will also provide answers to the unresolved questions of schizophrenic speech disorders and hence neologisms.]

Clinical Neuroscience

[Postoperative cerebroventricular collapsus]

ZOLTÁN László, NÉMETH Cs. Márta

[1. Clinically and pathologically verifically, 8 PCCs were detected in 7 infra-, 1 supra-tentorial tumors. 3 exited due to PCC, 1 later due to tumor. 4 of our patients were alive and had recovered relative to the biological value of the tumor. 2. Due to the severe disease of PCC, we recommend preventive ventricular drainage and, if the type of surgery and the biological shape of the tumor allow, accurate suturing, especially in posterior scala surgeries. 3. In the case of postoperative hyperthermia, sensory disorders, convulsions, sudden onset of otherwise unjustified paresis, we have to think about PCC, which can be easily diagnosed and treated with the help of ventricular drainage, resp. 4. Ventricular drainage is generally an excellent and secure tool for postoperative monitoring of intraventricular pressure conditions, especially from a differential diagnostic point of view. 5. In the case of PCC, rapid and lasting results can only be expected from filling the ventricular system, which is recommended to be adjuvanted with parenteral fluid intake, aided by Trendelenburg position.]

Clinical Neuroscience

[Foreign Language Summaries]

[A summary of the articles published in the issue in Russian and German]

All articles in the issue

Related contents

Lege Artis Medicinae

[Feeding and eating in infancy and early childhood part II. - Breastfeeding, complementary feeding and weaning in the Large-sample of the “For Healthy Offspring” project]

SZABÓ László, SCHEURING Noémi, DANIS Ildikó, NÉMETH Tünde, VÁRADY Erzsébet

[INTRODUCTION - Complementary feed-ing is the transitional period from exclusive breastfeeding to family foods, while breastfeeding is continued. It should be started, when breastmilk itself no longer meets the infant’s nutritional requirements, ideally at the age of around 6 months. SUBJECTS AND METHODS - In the Healthy Offspring project self reported questionnaires were received from 1133 parents of 0-3 year old children. Comple­mentary feeding practices and issues of weaning were analyzed. RESULTS - In our sample complementary feeding was started at the age of 5.5±1.8 months. 6% of infants younger than 4 months and about two third of infants at the age between 4 and 6 months were started on complementary feeding. 32% of the 7-12 month old infants were continued on breastfeeding. The proportion of breastfed infants and young children in the 12-24 and 25-36 month age group was 24% and 5.5% respectively. The daily feeding frequency of breastfed infants was 6.7±1.6. The infants and young children, who were breastfed along with complementary feeding were feeding 5.6±1.5 times/day. After completed weaning the range of feeding frequency was limited to 4.9±0.9 occasions/day. 60.4% of mothers regarded their feeding style on demand, while 39.6% on set schedule. 16% of mothers reported that their child had feeding difficulties. CONCLUSIONS - Complementary feeding indicators should be part of infant feeding data collection, such as time of introduction of complementary food, feeding frequency, food consistency, energy density of food and safe preparation. Responsive feeding is part of responsive parenting and should be promoted, along with continuing breastfeeding at least till one year of age, and for as long as mother and infant wish to continue. ]

Lege Artis Medicinae

[Organic and non-organic perspectives in feeding and eating disorders under three years of age]


[Providing optimal nutrition to infants and toddlers is a critical issue for both parents and experts. Besides the quality and quantity of food, indications of feeding behaviour such as feeding method and acceptance by the child are also crucial when determining feeding issues. The development of self-feeding is a significant part of the healthy somatomental development of a toddler between the age of 0-3 years. Efficient treatment of infants and toddlers with feeding disorders is often challenging in clinical practice. These symptoms frequently appear together with additional behaviour disorders, therefore functional reasons have to be taken into consideration in such cases. Due to the complexity of manifestations, applying tools beyond me­dical competence and involvement of special related professions are necessary. The general diagnostic systems of BNO-10 (International Classification of Diseases) and DSM-V (Statistical Manual of Mental Disorders) which are also applied in our country cannot be used appropriately for clear classification of early childhood feeding disorders and for examination of their backgrounds. DC:0-3R (Diagnostic Classi­fication of Mental Health and Develop­men­tal Disorders of Infancy and Early Childhood- Zero to Three), generally used in Anglo-Saxon countries, can be considered as a complex diagnostic system. Using the DC:0-3R classification system (1), we will present six types of feeding disorders affecting children between the age of 0-36 months in which organic and functional origins have been examined as well. In our article we argue for the complex, psychosomatic interpretation and treatments of early childhood feeding disorders.]

Clinical Neuroscience

Secretory meningioma with bone infiltration and orbital spreading

GARZULY Ferenc, KÁLOVITS Ferenc, TOMPA Márton, TAKÁTS Lajos, SOMOGYI Katalin, KÁLMÁN Bernadette

Secretory meningioma is a rare form of meningiomas which differentiates from the meningothelial subtype. It is characterized by significant peritumor edema and distinct immunohistochemical and molecular genetic profiles. We present a middle aged female patient with secretory meningioma infiltrating the orbital bone from the primary cranial base location and causing exophthalmos, features rarely described with this tumor. Surgical resection was challenging because of the associated brain swelling and rich vascularization of the tumor. Imaging and immunohistochemical studies revealed characteristic hallmarks of secretory meningioma. While histologically it was a benign tumor, due to the orbital bone and soft tissue infiltration, postoperative management of neurological sequelae was challenging. This case highlights distinctive clinical, imaging and histological features along with individual characteristics of a rare form of meningiomas.

Lege Artis Medicinae

[Neuropsychiatric complications of COVID-19 infection]


[Initially, the studies of COVID-19 infection focused primarily on the acute and subacute somatic symptoms of limited duration, but later on with the spread of the pandemic the scope was extended to prolonged symptoms recognized as complications. Data are mounting about after-effects in circulation, respiration, coagulation, problematic outcomes in rheumatology, dermatology, ophthalmology, as well as about the acute and prolonged symptoms of the dysfunctional central nervous system. Initially, sporadic case reports, later results of population based studies and animal models were available, and the first systematic review articles were emerging during preparation of our survey. Lesions of the central nervous system may manifest themselves both in neurological symptoms and diseases or psychiatric complaints and syndromes. The scale of symptoms is broad, the pathomechanisms are not perfectly mapped thus all therapeutic approaches are in their infancy yet. Epidemiological data of neuropsychiatric complications are incomplete for the time being though they have been rapidly becoming more accurate. Conservative estimates assume tens of millions of people affected worldwide. More time is necessary to assess the persistence or improvement of the prolonged symptoms. Besides every efforts to block the spread of the virus, the utmost importance is to analyze the effects of the virus on the central nervous system and to develop effective treatment strategies. According to our current knowledge, the pathomechanism of neuropsychiatric complications is multifactorial. Beyond the direct deleterious effect of the virus on neuronal and glial functions, more important is that the serious consequences of cerebrovascular dysfunction and poor oxygenation have to be taken into consideration together with extended and prolonged systemic immunological processes, which markedly harm the brain tissue, notably neurons, axons, synapses and glia cells. Based on a non-systematic lite­ra­ture review our work details these me­chanisms and addresses therapeutic options as well. ]

Clinical Neuroscience

[The evaluation of paroxysmal events in neonates and infants]

NAGY Eszter, HOLLÓDY Katalin, FARKAS Nelli

[Introduction - Differential diagnosis of neonatal and infantile seizures based only on inspection poses a challenge even for specialists. Aims - To investigate the evaluations of neonatal and infantile paroxysmal events based only on inspection. Research question - Is there any difference in the opinion of neonatologists, paediatric neurologists and neurologists about the assessment of common paroxysmal events in infancy? Patients and methods - Video recordings about paroxysmal movements of 15 neonates or infants (aged 2 days- 5 months) were displayed for 47 paediatric neurologists, 35 neonatologists and nurses working in Neonatal or Perinatal Intensive Care Units and 43 neurologists. They had to decide without knowing the past medical history or EEG results whether events presented were epileptic or nonepileptic in nature. Results - Answers of neonatologists and paediatric neurologists were correct in 67% of cases (824/1230), no significant difference was found between their results. The largest uncertainty was in the judgement of discrete hand movements and very rapid clonus with epileptic origin, they were judged correctly by only one third of participants. The result of neurologists was only slightly, but not significantly different from that of paediatric neurologists. Conclusion - In most cases, the correct diagnosis of neonatal and infantile paroxysmal events requires video-EEG recording. No significant difference was revealed between the evaluation of neonatologists and paediatric neurologists about the differential diagnosis of movements. The ongoing cooperation of paediatric neurologists and neurologists going back to several decades facilitates the shaping of a common perspective.]