Introduction: Spondylodiscitis is a rare inflammatory disease of the spine. Its symptoms are caused by local inflammatory destruction, toxic, direct nerve root and spinal cord compression. Typical symptoms are severe spinal pain, fever and neurological deficit depending on the location. It can be diagnosed by MR and laboratory tests.

Aims: The aim was to process data from patients treat- ed with spondylodiscitis Neurosurgery and Neurointer- ventional Clinic Budapest. In assessing their post-treat- ment condition and the outcome of surgery, we wanted to identify factors that may have influenced the outcome, affected their quality of life.

Methods: The data collection had two phases. Based on previous documentation, an ASIA scale score was calculated from their physical condition. According to this, patients were divided into 5 categories depending on their neurological deficit. Later, we contacted the pa- tients by telephone and again classified them into ASIA scale categories and completed a Functional Indepen- dence Measure questionnaire. Data were analysed using SPSS software, Shapiro-Wilk test, Spearman correlation, Mann-Whitney U test, Kruskal-Wallis test and khi2 test.

Result: The study enrolled 48 patients. 7 patients had worsening, 19 patients had no change and 22 patients had improvement according to their ASIA scale score. By the time of enquiry, 14 patients had died.

Significant correlation with treatment outcome was found for the following parameters (FIM score, ASIA scale change): age (p=0.022), Charlson comorbidity in- dex (CCI) (p=0.005), cervical location (p=0.046), thorac- ic location (p=0.009), lumbar location (p=0.004), number of segments affected (p=0.019), ASIA scale score before treatment (p=0.037). Surgery does not significantly im- prove outcome but seems to have a good effect on ASIA scale change.

Conclusion and Funding: Although the type of treat- ment did not significantly affect the outcome, the change in ASIA scale score was smaller in the conservatively treated group, and further patients are being enrolled to investigate this. Predisposing factors for worse outcome were older age, higher CCI, cervical and lumbar loca- tion, higher number of affected segments and lower ASIA scale score before treatment.