Lege Artis Medicinae

[Xamoterol in severe heart failure]

MATOS Lajos1

FEBRUARY 24, 1993

Lege Artis Medicinae - 1993;3(02)

[The two groups did not differ from each other in terms of improvement in clinical symptoms. Using a visual analogue scale and the Likart questionnaire, breathlessness appeared to be relieved with the active agent, but the duration of exertion or exercise capacity was found to be the same. Exercise-induced tachycardia and blood pressure elevation were attenuated with xamoterol (p < 0.01). The drug showed no arrhythmogenic effect. At 100 days after randomisation, 32 patients in the xamoterol group (9.1%) had died, compared with 6 (3.7%; p=0.02) of those treated with placebo.]

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