Lege Artis Medicinae

[The role of prostacyclin in the function of the gastric mucosa]

BÁLINT Gábor Sándor1

JULY 29, 1992

Lege Artis Medicinae - 1992;2(07)

[The intracellular effect of exogenously admi nistered prostacyclin in the gastric mucosa seems to be a polyphasic one, namely: 1. effect on the cyclic nucleotide (CAMP, CGMP) turnover, 2. effect on the calmodulin-content, 3. DNA and RNA changes 4. influence on protein synthesis 5. new cell formation. Besides the endogenous prostacyclin exerts a natural protection against damaging noxae, thus maintaining the physiological integrity of the mucosa. ]

AFFILIATIONS

  1. Szent-Györgyi Albert Orvostudományi Egyetem Ideg- és Elmegyógyászati Klinika, Klinikai Farmatológiai Laboratórium, Szeged

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