The aim of this study is to comprehensively determine the types of affected fibers in Parkinson’s disease (PD) patients by employing nerve conduction studies (NCS), sympathetic skin response (SSR) examinations, and current perception threshold (CPT) testing and to analyze the correlation between levodopa use and nerve involvement. This retrospective study included 36 clinically diagnosed PD patients who were recruited between January 2018 and April 2019.

Immune-checkpoint inhibitors (ICI) are effective drugs in cancer treatment that block immune checkpoints and stimulate an attack on cancer cells. However, various side effects were reported with ICIs. Peripheral nervous system (PNS) side effects are three times more frequent than those in the central nervous system. A 63-year-old male patient was admitted to our department with a 10-day history of dyspnea, diplopia, and generalized weakness.

Gliomas are the most common primary malignant central nervous system tumors in adults, exhibiting a poor prognosis. Indoleamine 2, 3-dioxygenase-1 has important functions in cancer immunotherapy due to its role in escaping cancer cells from the immune system. In this study we purposed to evaluate the correlation between IDO-1 expression and clinicopathological parameters in gliomas, and whether IDO-1 can be a prognostic marker.

Fibrinogen to albumin ratio (FAR) is thought to have a predictive effect in diseases such as cancer and myocardial infarction. We aimed to eluci­ date the prognostic value of FAR in ischemic stroke patients who underwent mechanical thrombectomy. A total of 103 patients hospita­ lized for acute stroke who underwent me­ chanical thrombectomy within 6 hours of symptoms’ outset have been analyzed retro­ spectively. Stroke severity was interpreted via the National Institutes of Health Stroke Scale (NIHSS) score during the neurological examination

[Leukodystrophies, a heterogeneous group of brain and spinal cord dis- orders, often pose challenges in establishing molecular etiology. Vanishing White Matter Disease (VWMD) is a rare subtype of leukodystrophies presenting with characteristic clinical and MRI features, nevertheless, achieving diagnostic certainty requires genetic studies. Our patient is a nine year old girl, who developed progressive gait difficulties at around 3-4 years of age. ]