Lege Artis Medicinae

[Resection of colonic polypoid cavernous hemangioma with help of rubber rings]

ÁCSNÉ Tóth Andrea1, LUKOVICH Péter1, LAKATOS Péter László2, KARDOS Magdolna3, ARANY Andrea Szilvia4, HARSÁNYI László1

MARCH 20, 2014

Lege Artis Medicinae - 2014;24(03)

[INTRODUCTION - Cavernous hemangioma is a benign, rare disorder, usually localized in the distal part of the gastrointestinal system. CASE REPORT - In a 19-year-old woman treated for Crohn’s disease localized to the colon, a polypoid lesion was found during routine colonoscopy. The lesion appeared to be vascularized, purple in color and could be localized 25 cm above the anal sphincter. MSCT examination confirmed vascularization of the lesion. Considering the high risk for severe bleeding, resection was performed with surgical assistance. At first, two rubber rings were placed around the polypoid lesion. Thereafter 1 ml of epinephrine was injected into the neck of the lesion above the rubber rings, followed by polypectomy with a standard hook. No complications were present during the observation period. Histological examination of the polypoid lesion confirmed it to be cavernous hemangioma. CONCLUSION - On the basis of previous cases and the present case there might be a connection between inflammatory bowel disease and the development of cavernous hemangioma. We have not found any previous reports of a similar application of rubber rings. However, in cases where the risk of bleeding is high, this method is safe and easy to apply.]

AFFILIATIONS

  1. Semmelweis Egyetem, I. Sz. Sebészeti Klinika
  2. Semmelweis Egyetem, I. Sz. Belgyógyászati Klinika
  3. Semmelweis Egyetem, II. Sz. Patológiai Intézet
  4. Egyesített Szent István és Szent László Kórház-Rendelôintézet, Központi Radiológia

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[Analysis of the knowledge on cervical cancer and attendance indicators of cervical screening]

VAJDA Réka, KARAMÁNNÉ Pakai Annamária, ÉLIÁS Zsuzsanna, SÉLLEYNÉ Gyuró Mónika, TAMÁS Péter, VÁRNAGY Ákos, KÍVÉS Zsuzsanna

[OBJECTIVE - The study aims to explore knowledge on cervical cancer and cervical screening among women with 9-14 yearold daughters, and learning the attitudes towards screening, the motivation of attendance at or absence from screening. DATA AND METHODS - A quantitative, cross-sectional study was conducted using our own questionnaire in the town Nagyatád in 2012. Study participants included women who had 9-14 year-old daughters and a registered home address in Nagyatád. We received valid responses from 186 people (response rate: 75.3%). RESULTS - The interviewed women’s knowledge on cervical cancer differed significantly depending on their age, education, marital status, and economic activity. Only 45 women with higher education (p=0.043) were considered to be well informed on the subject. However, their willingness to participate in cancer screening was more favorable than their knowledge, 96.2% of the women claimed to attend an annual cancer screening. The average age of respondents was 20.92 years at first visit. CONCLUSIONS - Although the participation rate was much higher compared with that in previously published studies, it is of great importance to increase the mothers’ knowledge on cervical cancer and the factors that promote its development, so that they can pass their knowledge to their children and strengthen their protection against one of the most common sexually transmitted viral infection and the development of cervical cancer.]

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Lege Artis Medicinae

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[The role of hepatitis C virus in the development of non-Hodgkin lymphomas]

SULYOK Mihály, MAKARA Mihály, ÚJHELYI Eszter, VÁLYI-NAGY István

[There is a growing body of evidence for the association between chronic hepatitis C virus infection and certain subtypes of Bcell non-Hodgkin lymphoma. The development of a lymphoid malignancy is usually preceded by cryoglobulinaemia. Here, we summarise the most important epidemiologic data, and the possible molecular mechanisms of HCV-associated lymphomagenesis. The direct oncogenic effect of the virus has not been proven, but chronic antigenic stimulation maintained by replication and viral lymphotropism might both contribute to the development of lymphomas. It should be emphasised that elimination of the hepatitis C virus can halt this process in case of cryoglobulinaemia and low-grade malignity (usually marginal zone lymphomas). In these cases, antiviral therapy might be a useful alternative of conventional immune-chemotherapy. Thus, a collaboration between haematologists and hepatologists might be a great step forward in the treatment of these diseases. It is still not established whether interferon-based short-course therapies and interferon-free regimens are also effective in the treatment of associated lymphomas.]

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[INTRODUCTION - Very rarely do colonic diverticula grow enourmously - from 3-4 cm upto 15-20 cm in diameter - causing diagnostic difficulties. PATIENT AND METHODS - The authors present a case of an elderly male patient where the ultrasound examination accidentally revealed irregularity in a part of the sigmoid colon with thickened wall. This finding was then examined by colonoscopy, colonography (double contrast barium enema) and CT. Two giant diverticula, measuring 4-5 cm in diameter, arising from the sigmoid colon were demonstrated. Considering the old age of the patient and the lack of clinical symptoms, the affected part of the sigmoid colon had not been surgically resected. CONCLUSION - Giving a general overview on the pathogenesis, presentation and differential diagnosis of colonic diverticula, the authors emphasise the importance of colonography. Also, as far as the authors know, this is the first Hungarian report on giant colonic diverticulum.]