Lege Artis Medicinae

[Principles of antibiotic use in clinical practice]

SZALKA András

MAY 20, 2003

Lege Artis Medicinae - 2003;13(04)

[There has been a very significant reduction in morbidity and mortality associated with the use of antibiotics since they were first introduced, but, there has also been a concomitant rise in resistance among pathogens over the past 50 years. Moreover, antibiotics are sometimes associated with adverse events and their use can account for a significant proportion of the cost of treatment of some conditions. To ensure the optimal use of antibiotics doctors should use the most appropriate antibiotics to stop the spread of infection. In choosing the appropriate antimicrobial agent for the therapy of a certain infection several key factors must be considered: the most likely identity of the infecting organism, the potential antimicrobial susceptibility of the infecting organism and the host factors that influence the response to therapy. This publication is designed to introduce the concept of appropriate antibiotic therapy and how it can minimise the emergence of antimicrobial resistance while ensuring optimal patient management.]

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