Lege Artis Medicinae

[Neuropathic pain: spotligth on amitriptyline]

FEHÉR Gergely1, POHL Marietta1, KAPUS Krisztián1, GOMBOS Katalin2, PUSCH Gabriella3, MÁK Kornél1, KOLTAI Katalin4, BANK Gyula5, KÓSA Gábor1, VARJASI Gábor1, TIBOLD Antal1

NOVEMBER 15, 2019

Lege Artis Medicinae - 2019;29(11)

DOI: https://doi.org/10.33616/lam.29.046

[The management of neuropathic pain is a challenge both for patients and medical professioners. A novel approach is recommended for its management based on the novel neurobiological results of pain research. Multidisciplinary teams and medical consensus are required due to the variety of symptoms and concomittant psychopathology. This approach allows us to avoid extensive diagnostic and trerapeutic workups and appropiate treatment for our patients. Most extensive evidence is available for pharmacological treatment, and currently recommended first-line treatments include antidepressants (tricyclic agents and serotonin-norepinephrine reuptake inhibitors) and anticonvulsants (gabapentin and pregabalin). The aim of our review was to collect articles focusing on the efficacy of the most widely available and cheapest tricyclic agent, amitriptyline in different neuropathic pain conditions. ]

AFFILIATIONS

  1. Pécsi Tudományegyetem Klinikai Központ, Foglalkozás-egészségügyi és Munkahigiénés Központ
  2. Pécsi Tudományegyetem Klinikai Központ, Laboratóriumi Medicina Intézet
  3. PTE KK, Neurológiai Klinika
  4. Pécsi Tudományegyetem Klinikai Központ, I. Sz. Belgyógyászati Klinika
  5. Kecskeméti Kórház, Krónikus Belgyógyászati Osztály

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