Lege Artis Medicinae

[Misleading tumor markers in pulmonary carcinomas]

CIFRA János, BOGNER Barna, HELF László, SZÉKELYI Katalin, KÁLMÁN Endre, SÁPI Zoltán

DECEMBER 20, 2010

Lege Artis Medicinae - 2010;20(12)

[Lung cancers are the leading cause of tumorous mortality and the most frequent tumor in the 40- 70 years age range. The chance for cure in lung cancers is much higher in the early stage of disease so the early diagnosis has a paramount importance. Although many tumor markers are used in the diagnosis of malignant tumors, their specificity raise some doubts. The increased level of hCG is traditionally connected with choriocarcinomas and the CA 19-9 antigen is connected with gastrointestinal carcinomas. The production of hCG and CA19-9 is extremely rare but well established fenomenon in pulmonary carcinomas. In some cases of pulmonary cancers various tumor markers are produced, causing differential diagnostic difficulties. Through our cases and literature review we wanted to draw the attention of the organ unspecificity of these tumor markers.]

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