Lege Artis Medicinae

[Maurice Ravel’s Illness ]


DECEMBER 18, 2013

Lege Artis Medicinae - 2013;23(12)



Further articles in this publication

Lege Artis Medicinae

[The Triumph of Ideal in the Museum of Fine Arts ]

NAGY Zsuzsanna

Lege Artis Medicinae

[Diagnosis and treatment of melanoma based on European interdisciplinary guideline]

VAJDA Adrienne

Lege Artis Medicinae

[Life is Short and Unique ]

SZÉLL Kálmán

Lege Artis Medicinae

[Mirror neurons and interpersonality in the paradigm of embodied mind]


[In this paper, our aim is to scrutinise the psychology and phenomenology of interpersonal relationships from an interdisciplinary viewpoint. This multi-perspectival examination has a key concept: we critically discuss the interdisciplinary dialogues and philosophical appraisals regarding the issue of mirror neurons. Empathy and resonance phenomena have philosophical, psychological, and biomedical importance. Our paper, by applying certain philosophical and empirical results of the overarching paradigm of embodiment, attempts to shed light on several semantic problems, which could come up with respect to the function of mirror-neurons. In conclusion, we would like to attempt to utilise the results of contemporary phenomenology in order to clear some semantic problems, considering the features of mirroring and resonant behaviour.]

Lege Artis Medicinae

[Vitamin D treatment: hormone therapy for patients who need it or simply a supplementation for everyone?]


[Various medical associations issue different recommendations for the prevention and treatment of vitamin D deficiency. These significant differences are partly explained by the different definition of normal vitamin D level and the use of completely different mathematical models to predict the increase in vitamin D level as a response to therapy. According to the Institute of Medicine (IOM), the target vitamin D level is 20 ng/ml, whereas the Endocrine Society (ES) recommends 30 ng/m as the miminum target value. According to the ES, a 1 ng/ml increase of vitamin D level can be reached by a daily intake of 100 NE, while the IOM recommends 3.6 ng/ml. Moreover, the IOM states that the effect of therapy on serum level is nonlinear. These differences show that the ES and IOM have different views on the risk of adverse effects. The IOM recommends 400 IU vitamin D daily for children younger than 1 year, 800 IU for those above 70 years and 600 IU/per day for everyone else. The ES recommend 400-1000 IU daily for all infants and 1500- 2000 IU for adults. Screening, however, is not recommended by either society. To decrease uncertainty concerning the side effects of higher-dose vitamin D treatment, it is important to understand, use and support the function of the pharmacovigilance system of the pharmaceutical industry that manufactures and markets various (prescription, over-the-counter) preparations. This is what the author aims to highlight in the second part of this article. Using this system, both the doctor and the patient can help support and accept the justification of higher-dose vitamin D therapy.]

All articles in the issue

Related contents

Lege Artis Medicinae


STIRCZER Gabriella

[The congenital or acquired damage of the lymphatic system can lead to the increase of the interstitial fluid in the affected extremity which can lead to chronic lymphoedema. Congenital lymphoedema is relatively rare. The interest in chronic lymphoedema is relatively high as the frequency of tumours is increasing (with surgical and irradiation therapy in the background) and of the growing numbers of the secondary lymphoedema cases due to chronic venous insufficiency in the extremities. The diagnosis and early treatment of the disease is important because the illness without therapy can be progressive and lead in severe complications, such as permanent disability of the patient. In the last 10-15 years the conservative therapy protocol of chronic lymphoedema has been introduced in Hungary and the necessary appliances are financed by the National Health Service (OEP). However, it is unfortunate that there are not enough lymphoedemic centres and patients often visit the outpatient departments only after the advice of a fellow-patient. These days, a great proportion of the patients are without treatment and in many cases the therapy can only concentrate for the prevention of the complications.]

Lege Artis Medicinae


PIKÓ Bettina, PICZIL Márta

[INTRODUCTION - Studies have shown that work environment has a significant impact on workers’ health status and their reactions to stress, which may contribute to the development of illness, or, among health care staff, to burnout syndrome. The goal of the present study was to look at the relationship between psychosocial work environment and self-perceived health in a sample of health care staff living in Szabadka (Subotica, Serbia). METHODS - There were 253 health care workers in the study group. The majority were registered nurses, head nurses and assistants (together, 80.1%). Self-reported data were collected using a questionnaire on self-perceived health, frequency of psychosomatic symptoms, work shift pattern, and psychosocial work environment (e.g., the frequency of emotionally provoking situations or the level of dissatisfaction with work). RESULTS - Health care workers reported frequent experience of emotionally provoking situations. However, they often lack a connection network that would provide effective social support in these situations. In addition to the frequent occurrence of emotionally provoking situations and the lack of social support, voluntarily chosen extra work, shift work, and the low level of work satisfaction influence negatively their self-perceived health. CONCLUSIONS - The psychosocial work environment has a significant impact on the health care workers’ self-perceived health and the occurrence of psychosomatic symptoms. It would be necessary for health care workers to learn skills and techniques that help them cope with emotionally hard situations.]

Journal of Nursing Theory and Practice

[The importance of patient education and ILCO clubs in the rehabilitation of stoma patients]


[Aim of the study: The author aims to reveal and propose a solution for the flaws in the education of stoma patients, especially with regard to patient education at the Department of Surgery in Szeged. She examined the opinions, attitudes and knowledge of stoma patients regarding patient information, rehabilitation, and the extent to which they participated in the self-help groups. Methodology and sample: In the course of the quantitative descriptive research a questionnaire-based survey was conducted among the stoma patients treated and cared for at the institute (N=96). The data was processed using mathematical statistical methods. Results: 83% of the patients received lifestyle information at the institute, which helped them to accept their illness, and 99% of them were taught about stoma care at the clinic. The patients that participated in the training course, with the assistance of the stomal therapy nurse, were better able to accept their disease. The proportion of those participating in the self-help group was 51%, despite the fact that 65% of those asked regarded the ILCO club as useful. Conclusions: The provision of lifestyle information and the development of patient education at the department have an important role, because the majority of the patients express no demand for club membership. The author also takes the opportunity to highlight the importance of a holistic and multidisciplinary approach to the nursing of stoma patients. ]

Clinical Neuroscience

Health anxiety mediates the connection between somatosensory amplification and self-reported food sensitivity

ELIESON M. Linn, DÖMÖTÖR Zsuzsanna, KÖTELES Ferenc

Background - The frequency of self-reported food sensitivity (SFS) is increasing, and has a negative impact on the well-being and everyday functioning of the affected people. A considerable proportion of SFS cannot be medically explained. The lack of knowledge of its origin and treatment causes further stress in those affected. Purpose - This study aims to get a better understanding of the psychological background of the condition. Methods - A non-representative community sample (N=335; age: 35.1±13.18 yrs; 75.8% female) completed an English on-line questionnaire assessing somatosensory amplification, health anxiety, modern health worries (MHWs), beliefs concerning the scientific validity of complementary and alternative medicine (CAM), holistic beliefs on health and illness. Results - In multiple binary logistic regression analyses, SFS were associated with CAM related beliefs, somatosensory amplification, and health anxiety after controlling for age and gender. The connection between somatosensory amplification and SFS were completely mediated by health anxiety. No differences between the two groups were found with respect to MHWs, worries about the harmful effects of various artificial components in food, and holistic health beliefs. Discussion: More positive attitudes toward CAM might be based on the lack of conventional treatment, rather than on higher levels of MHWs or a more holistic worldview. Both the existence of symptoms and the presence of health anxiety might be needed for the development and maintenance of SFS. Conclusions - The findings support the notion that somatosensory amplification and health anxiety might play a role in the development and maintenance of SFS.

Clinical Neuroscience

[Alemtuzumab therapy 2017]

BIERNACKI Tamás, BENCSIK Krisztina, SANDI Dániel, VÉCSEI László

[Multiple sclerosis (MS) is a chronic, immune-mediated disease of the central nervous system comprising of inflammation, demyelinisation and neurodegeneration. The natural history of MS is heterogenous. Owing to the vast range and severity of the symptoms MS can cause the effect of the disease on one’s cognitive and physical status is unpredictable. According to the new, phenotype based classification two subgroups can be distinguished; relapsing-remitting (RR) and progressive MS. Relapsing-remitting MS can be further divided into active and inactive disease. The activity of the disease can be proven either clinically and/or by radiological means. A patient’s disease is considered inactive, if it fulfills the criteriae set in the “no evidence of disease activity-3” (NEDA-3) concept, meaning that no progression can be seen on the MRI scans, the patient is relapse free and there is no worsening on any disability scale. Nowadays a paradigm shift can be seen in the treatment of MS. The aim of this shift is to provide each and every patient with the most potent medication best suiting his/her illness as soon as possible. Alemtuzumab offers a great option as either a first line treatment or as escalation therapy for patients with a highly active disease. The efficacy of alemtuzumab was proven in two phase III trials (CARE-MS I, II), where it was compared to subcutaneous interferon b-1a, administered three times weekly. In both studies alemtuzumab was superior to subcutaneous interferon b-1a in terms of relapse rate reduction, in all scouted MRI parameters. In the CARE-MS II trial it was found superior in terms of progression slowing. In the studies’ first 2 years 32% and 39% of the alemtuzumab treated patients managed to achieve the NEDA-3 state (data from CARE-MS II and I respectively). At the end of the 4 year extension of both studies these numbers have increased to 60% and 55% respectively. The aim of our synopsis is to suggest neurologists an evidence based guideline, a therapeutic algorithm to be used when they give their MS patients the very best, personalised treatment, and also to appoint the recently introduced alemtuzumab to its proper place in the algorithm.]