Lege Artis Medicinae

[Insulin: alfa and omega]

KIS János Tibor1, BALOGH Bernadett1, KISS Zsófia2, SCHANDL László1

DECEMBER 17, 2021

Lege Artis Medicinae - 2021;31(12)

DOI: https://doi.org/10.33616/lam.31.044

Review

[Type 1 diabetes (T1DM) is caused by the autoimmune death of insulin-producing β-cells. In the background there is by all probability the primary antigen (if the theory of primary antigen is correct) the insulin itself or the proinsulin. However, treatment of T1DM is virtually equivalent to the insulin treatment. The earlier we recognize T1DM and start treatment, the better gly­caemic results we achieve, the more likely we can maintain all functional β-cell stocks. Insulin also plays a key role in the immunopathogenesis, development and treatment of T1DM, thus insulin is the alpha and omega in this condition.]

AFFILIATIONS

  1. Észak-Közép-Budai Centrumkórház, Új Szent János Kórház és Szakrendelő, Diabetológia
  2. Betegápoló Irgalmas Rend, Budai Irgalmasrendi Kórház, Diabetológia, Budapest

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