Lege Artis Medicinae


VIZI Éva, CSOMA Zsuzsanna, HUSZÁR Éva

DECEMBER 20, 2003

Lege Artis Medicinae - 2003;13(08)

[Exercise-induced bronchoconstriction describes the transient narrowing of the airways occurring during and most often after vigorous exercise. The mechanism of exercise-induced bronchoconstriction remains elusive, although airway drying and cooling plays a prominent role. The severity of this reaction depends on the temperature and the water content of the inspired air, the type and concentration of air pollutants inspired and the intensity of the exercise. Diagnosis of exercise-induced bronchoconstriction should include baseline spirometry followed by an exercise challenge test. The exercise can be a free-running test or a laboratory based test using a cycle-ergometer or a treadmill. Pre- and post-exercise pulmonary function should be compared, 10%-15% postexercise fall in forced expiratory volume in 1 second (FEV1) is used as a diagnostic criteria (10% in laboratory test, 15% in free-running test). Heat loss, water loss, post exertional airway rewarming and the role of several mediators have been proposed as possible mechanisms responsible for the airway obstruction induced by exercise. Exercise-induced bronchoconstriction can be easily diagnosed and treated in the majority of patients. When properly treated, asthmatic individuals should be able to participate or compete in the majority of sports.]



Further articles in this publication

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SZOLNOKI Erzsébet, DÉVÉNYI Katalin, DANKÓ Enikő, DEZSŐ Balázs, SZILASI Mária

[The aim of the authors was to overview the different forms of diffuse interstitial lung disease based on newly established radiological (HRCT) pattern and histopathological analysis beyond the clinical picture. Idiopathic pulmonary fibrosis is emphasized having also historical importance and possible therapeutic antifibrotic interventions are discussed as well.]

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TÚRY Ferenc, LUKÁCS Liza, RÁCZ Olimpia, HORVÁTH Krisztina

[Eating disorders show an important change in the last few decades concerning their frequency and clinical picture, as well. Besides bulimia nervosa, which was described two decades ago, muscle dysmorphia appeared ten years ago as a special body image disorder of males, regarded as a reverse form of anorexia nervosa in females. Eating disorder, body builder type was described only in 2000, meaning an overconcern about the body composition and muscle mass, accompanied by strict dieting rules. Another type of these disorders was described also in 2000, the nontraditional gender role in women, which is a strong preference for male characteristics and activities, the person being comfortable with her sex, while there is no intersex condition. This overview discusses the proposed diagnostic criteria and the role of some sociocultural factors in these recent disorders.]

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[Nobel Prize in Medicine for the Pioneers of MR Imaging]


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[The method of gradual limb lengthening plays a significant role in equalizing limb discrepancies, making dwarfs taller, correcting axial and other deformities coexisting with limb deficiency. Limb lengthening is carried out by one of two basic methods: diaphyseal lengthening with the Wagner unilateral distraction apparatus or metaphyseal lengthening with a series of rings and crossed K-wires. Gradual limb lengthening is presently having its golden days. At our institution 302 limb lengthening intervention were done between 1977 and 2002, 164 cases with Wagner, 137 cases with Ilizarov method, and one distraction epiphyseolysis. In average, 4.1 cm lengthening was achieved, 18.4% of the original length of the bone. The high incidence of complications was due to superficial infections at the entry points of the Kwires, infrequently worsening the outcome of the operation. Operative limb lengthening performed with appropriate indications and technique is a successful and rewarding area of orthopaedic surgery.]

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[The relentless increase of patients with kidney failure requiring renal replacement therapy has been documented world-wide. Recently, diabetic renal diseases has become the major cause of end-stage renal disease in the United States and in western Europe and is forecasted to become the most frequent cause of end-stage renal disease in Hungary. The most common renal lesion in type 1 as well as in type 2 diabetes is diabetic nephropathy. However, in the last few years numerous studies have demonstrated that there is a difference between patients with type 1 and those with type 2 diabetes in the expression and frequency of their renal disease. In type 1 diabetes a histological examination should only be made when a patient has features atypical of diabetic nephropathy and the indications of renal biopsy are well known. At the same time there is no agreement on renal biopsy indications in type 2 diabetes. In this review, we will summarise the characteristic features of diabetic nephropathy and other kidney alterations in the diabetic patient. Furthermore, we will raise the question of the renal biopsy indications and the more extensive use of the renal biopsy in type 2 diabetic patients for more effective prevention and treatment strategies.]

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