Lege Artis Medicinae

[Evaluation of bone mineral density in renal form of primary hyperparathyroidism]

CSUPOR EMŐKE1, SZŰCS János2, MÉSZÁROS SZILVIA2, LAKATOS Péter2, TÓTH EDIT3, HORVÁTH CSABA2

FEBRUARY 20, 2003

Lege Artis Medicinae - 2003;13(02)

[INTRODUCTION - The most frequent manifestations of primary hyperparathyroidism are renal stones or calcipenic osteopathy. The aim of authors was to examine how bones are affected (change of bone mineral density and frequency of fractures) in the renal form of primary hyperparathyroidism. METHODS - Mean age of the patients was 57 years (26 -81 years), (4 men, 33 women). Bone mineral density was measured in the lower third of the radius, femoral neck and lumbar 2-4 vertebrae by densitometers. Moreover, occurrence of fractures and biochemical parameters characteristic for hyperparathyroidism (serum parathyroid hormone levels, calcium, phosphorus, alkaline phosphatase, urinary calcium/ creatinine) were examined. RESULTS - Bone mineral density was normal in 6 cases, osteopenic in 10 patients and 21 patients had osteoporosis. Altogether five patients had fractures. Bone mineral density and biochemical parameters were not different in patients with or without fractures. CONCLUSIONS - Bone mineral density decreases in renal form of primary hyperparathyroidism even if there is no bone disease in the clinical picture. Therefore, bone mineral density measurement is advisable for every patient with hyperparathyroidism.]

AFFILIATIONS

  1. Budavári Önkormányzat Egészségügyi Szolgálata
  2. Semmelweis Egyetem, ÁOK, I. Belgyógyászati Klinika
  3. Flór Ferenc Kórház, Reumatológia és Fizioterápiás Osztály

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