Lege Artis Medicinae

[Diabetes mellitus and hypertension - Facts, questions and thoughts]

KERÉNYI Zsuzsa1, STELLA Péter1, TAMÁS Gyula2

OCTOBER 01, 2000

Lege Artis Medicinae - 2000;10(10)

[Using the new diagnostic criteria by WHO/ISH, the frequency of hypertension in type 1 diabetic patients is 15-61%, reaching 51-73% in type 2 cases. The combination of diabetes mellitus with hypertension increases the risks of stroke and cardiovascular diseases further compared to non-diabetic hypertensive patients. Authors review new recommendations concerning the diagnosis and treatment goals of hypertension in different types of diabetes mellitus. Most recent studies supporting these recommendations are also critically analysed. Theoretical advantages of new drugs and drug combinations in the therapy of hypertensive diabetics are reviewed. The strategy of treatment according to the cardiovascular riskprofile of diabetic patients is discussed in detail in the report. For the prevention of target-organ damage, the evidence based combination of ACE inhibitors and long-acting calcium channel blockers was strongly recommended. In about 70% of diabetic patients a combination of two drugs, in one-third of the cases a combination of three or four preparations seemed to be necessary, including low-dose diuretics and/or cardioselective beta-blockers. ]

AFFILIATIONS

  1. Diabétesz Gondozási Nemzeti Központ, Szent Imre Kórház, IV. Belgyógyászati Osztály, Önálló Diabétesz Részleg, Budapest
  2. Diabétesz Gondozási Nemzeti Központ, Semmelweis Egyetem ÁOK, I. Sz. Belgyógyászati Klinika, Diabétesz Részleg, Budapest

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