Lege Artis Medicinae

[Day-to-day blood pressure variability measured with home monitoring for the verification of succesful antihypertensive therapy]

KÉKES Ede, PAKSY András, KISS István

JUNE 01, 2015

Lege Artis Medicinae - 2015;25(04-05)

[The value of „day-to-day” blood pressure variability based on home blood pressure measurements for demonstrating of successful antihypertensive treatment. Authors analyzed the effect of antihypertensive therapy on the blood pressure variability by day-to-day method based on home pressure measurements in a large number of hypertensive patients. During the four months observation period the mean blood pressure values were significantly decreased and the parameters of blood pressure variability were decreased as well, they reached the level of normal variability. The nowadays expected „double target values” has given us hope that we can successfully prevent the organ damages due to high blood pressure. The effects of some „drug family” and the drug-combinations to the blood pressure variability were analyzed. The RAS inhibitors (ACEI and ARB) reduced significantly the blood pressure variability, the ARB drugs more effectively. The ACEI agents combined with calcium antagonists or third-generation beta-blockers increased the normalization of blood pressure variability. Such effects were not observed with the ARB agents. Authors suggested the use of their method in every day practice. The guidelines also recommend this method.]

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