Lege Artis Medicinae

[Awareness of hypoglycaemia in diabetes mellitus: Prospective clinical-epidemiological investigations]

KERÉNYI Zsuzsa1, TAMÁS Gyula2, KEMPLER Péter3, VARGHA Péter4

FEBRUARY 09, 1991

Lege Artis Medicinae - 1991;1(03)

[In order to survey the frequency of hypoglycaemia and its awareness we investigated 91 insulin- treated diabetic women (48 pregnant and 43 non-pregnant) consecutively using 9 to 15 blood glucose measurements. Subjective hypoglycaemic symptoms of patients were registered by using a structured questionnaire. Biochemically proved hypoglycaemia has been found in two third of patients (62/91). One third of the patients had a loss of awareness, 23 had partial awareness and 19 were aware of hypoglycaemia. No significant difference were found according to age, diabetes duration, daily insulin dose/kg body weight, glycated haemoglobin levels and frequency of diabetic complications. Five standard cardiovascular autonomic reflex-tests were performed in 31 patients. Age, diabetes duration, frequency of diabetic complications of patients with evidence of autonomic neuropathy significantly surpassed that of having normal cardiovascular reflex-tests. Our results confirm from clinical-epidemiological aspect that hypoglycaemia unawareness is not invariably associated with cardiovascular autonomic neuropathy. ]

AFFILIATIONS

  1. Főorvos Tétényi úti Kórház II. Belosztály
  2. Egyetemi docens
  3. Egyetemi tanársegéd Semmelweis Orvostudományi Egyetem I. Belklinika
  4. Tudományos munkatárs Semmelweis Orvostudományi Egyetem Biometriai és Kliniko-epidemiológiai Munkacsoport

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