Lege Artis Medicinae

[A paradigm shift in healthcare]

TÖRŐCSIK Mária

JULY 14, 2008

Lege Artis Medicinae - 2008;18(06-07)

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Lege Artis Medicinae

[I Have Allergy]

dr. BERTA Gyula

Lege Artis Medicinae

[SPONTANEOUS RUPTURE OF THE SPLEEN IN PULMONARY FIBROSIS]

SZOLNOKI Erzsébet, DEZSŐ Balázs, SZILASI Mária

[INTRODUCTION - Splenic peliosis is a pathological entity; it is only mentioned in case reports in the literature. CASE REPORT - A 61-year-old man with hypertension and diabetes mellitus presented with effort dyspnoe that was subsequently found to be due to idiopathic pulmonary fibrosis by histological examination. During steroid therapy, a spontaneous splenic rupture developed, which the patient fortunately survived. There was no need for splenectomy, but the clinical course suggested splenic peliosis. CONCLUSION - In this case, splenic rupture was associated with idiopathic pulmonary fibrosis, a constellation that has not yet been reported. Nevertheless, it was an isolated rupture, with no similar haemorrhagic lesion of other parenchymal organs. In view of the literature data, beside primary disease steroid therapy and the coexisting diabetes may also have played a role in the development of the spontaneous splenic rupture.]

Lege Artis Medicinae

[Factors Indicating Success of Antiviral Treatment in Chronic Hepatitis C]

NEMESÁNSZKY Elemér

Lege Artis Medicinae

[Upper limb robotic exercise in patients with spastic haemiparesis]

FAZEKAS Gábor

Lege Artis Medicinae

[Scientific Digest]

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[Together for Healthcare?! LAM Club has Launched Again]

KÖBLI Anikó

Lege Artis Medicinae

[New treatment option for oral anticoagulation in the prevention of cardiogenic stroke - Focus on the RE-LY trial]

SZAPÁRY László

[Atrial fibrillation (AF) represents the most common cause of cardioembolic stroke. The prevalence of AF increases with age and affects 10% of elderly people. AF-related stroke is usually severe and has a high mortality. The risk of stroke can be estimated on the basis of risk factors accompanying AF and age. Patients with one of the highest risk are those with AF and previous TIA or stroke. Efficient prevention is achieved by chronic anticoagulation therapy. In clinical practice, the use of vitamin K antagonists (VKA) has been the only option. The use of these agents is limited for a number of reasons, and clinicians are especially reluctant to use them in elderly patients at high risk of stroke. Consequently, of the patients with AF for whom anticoagulant therapy is indicated, only about 50-60% receives such therapy, and only half of the treated patients achieves target INR values. More than 50 years after the introduction of warfarin, data of trials with the new direct thrombin inhibitor dabigatran have been published in the past few years. In this paper, we review the results of the phase III, international RE-LY trial, published in 2009, which evaluated the preventive efficacy dabigatran etexilate in patients with AF compared with warfarin at a therapeutic dose. On the basis of the results, dabigatran used at a dose of 2×110mg daily provides the same protection as warfarin, whereas at a dose of 2×150mg it provides a signiificantly more efficient protection from AF-associated stroke and systemic embolism. In addition to its excellent preventive effect, dabigatran tretament results in a significant decrease in the risk of intracranial haemorrhages, and of other major haemorrhages. On the basis of the results, dabigatran will probably change the current treatment paradigm in the stroke prevention in patients with AF, and its introduction can substantially increase the number of patients treated efficiently and safely.]

Journal of Nursing Theory and Practice

[Development the mental and physical health of the healthcare staff]

MISZORY Erika Viktória

[Objectives: To analyse, whether the mental and physical health of the healthcare staff can be influenced by movement therapy. Methods: Between May and July 2016 we held multiple movement therapy sessions within the healthcare staff of the the Hungarian Army Medical Center, Musculoskeletal Rehabilitation Institute in Hévíz. With the help of the so called General Health Questionnare I collected information about the mental state of the participants. This questionnaire included 12 questions and had to be filled out by each and every person alone. From the physical variables perspective I collected information from the staff in regards to the mobility of their spine. Microsoft Excel was used for the analysis of the data and to prove the significance of the variables, I used the T-probe method. Results: Majority of the participants has both internal medicine and musculosceletal problems, symphtoms and diseases. Though the psychic stress on them can be clearly seen, it can be treated with movement therapy efficiently. On the other hand, I could not find any significant change in the variables related to the spine-movements. Conclusions: With the help of regular movement therapy the mental state of the staff can be efficiently infleunced and improved. Further studies suggested a greater number of elements, for detected the physical changes.]

Clinical Neuroscience

[Plasticity of brain lateralization in epilepsy: fMRI studies]

KALMÁR Zsuzsanna és munkatársai

[Aims - This review is a summary of four studies investigating the effect of epileptic disturbance and other functional factors on the brain lateralization. Methods - Patients were investigated by functional MRI by using visual, sensorimotor, memory, and speech paradigms. Results - 1. Malformations of cortical development localized within speech centers induce contralateral speech reorganization in only 50% of cases. 2. Epileptic disturbance can induce a reorganization in language lateralization independent of the effect of lesion. 3. Bilateral epileptic activity can prevent a reorganization of memory functions contralateral to the seizure onset region. 4. Injury of the right upper limb can induce a left-to-right shift of language lateralization. Conclusions - Our results may have implication during neurorehabilitation process and neurosurgical interventions. Participation of malformations of cortical development in cognitive functions should keep in mind during surgery. Reorganization of speech- and memory functions should also be considered during operations of central nervous system.]

Lege Artis Medicinae

[Mirror neurons and interpersonality in the paradigm of embodied mind]

HORVÁTH Lajos, SZABÓ Attila

[In this paper, our aim is to scrutinise the psychology and phenomenology of interpersonal relationships from an interdisciplinary viewpoint. This multi-perspectival examination has a key concept: we critically discuss the interdisciplinary dialogues and philosophical appraisals regarding the issue of mirror neurons. Empathy and resonance phenomena have philosophical, psychological, and biomedical importance. Our paper, by applying certain philosophical and empirical results of the overarching paradigm of embodiment, attempts to shed light on several semantic problems, which could come up with respect to the function of mirror-neurons. In conclusion, we would like to attempt to utilise the results of contemporary phenomenology in order to clear some semantic problems, considering the features of mirroring and resonant behaviour.]