Lege Artis Medicinae - 2006;16(05)

Lege Artis Medicinae

MAY 21, 2006

[BETA-CELL DYSFUNCTION AND PROTECTION IN TYPE 2 DIABETES]

VÁNDORFI Győző, URICH Elemér

[Type 2 diabetes is caused by increased insulin resistance coupled with the disturbance of the secretion function of beta-cells. While the importance of insulin resistance has been emphasized in the last two decades, the pathogenetic role of beta-cell dysfunction has received less attention. Regarding this latter, several underlying mechanisms have been implicated, including increased secretory demand due to insulin resistance, glucose toxicity, lipotoxicity, islet cell amyloid deposition, and... tovább »

Lege Artis Medicinae

MAY 21, 2006

[LOWER LIMB PAIN OF VASCULAR ORIGIN]

MESKÓ Éva

[The paper describes the characteristics of limb pain associated with acute and chronic arterial occlusions, venous and lymphatic diseases, and underlines the importance of early diagnosis and treatment that may determine the fate of the limb. The type of leg ulcer developing as a complication of an arterial or venous disease can usually be diagnosed by the inspection of the leg. Symptoms that accompany venous thrombosis of the leg often pose serious differential diagnostic problems. The venous... tovább »

Lege Artis Medicinae

MAY 21, 2006

[ANTICOAGULATION IN OBSTETRICS]

DOMJÁN Gyula, GADÓ Klára

[The risk of thrombosis is increased about 5 to10 times during pregnancy and in the puerperium. Beside the classic risk factors, this is also due to special obstetrical causes. Delivery, especially Cesarean section further increases susceptibility to thrombosis. Prophylactic or therapeutic anticoagulant treatment can significantly reduce maternal and fetal morbidity and mortality. Just like in the non-pregnant state, subcutaneous low molecular weight heparin or intravenous or subcutaneous... tovább »

Lege Artis Medicinae

MAY 21, 2006

[THE COMPLEX EFFECT OF TREATMENT TARGETING THE OESTROGEN RECEPTORS IN POSTMENOPAUSAL WOMEN]

TAKÁCS István, LAKATOS Péter

[Hormone depletion after menopause results in the dramatic increase of the incidence of a number of diseases. It should seem reasonable to substitute female hormones to prevent or treat these disorders. However, hormone replacement therapy has not fulfilled the expectations in its current form. While the first large, prospective, randomized, controlled primary prevention trial showed a beneficial effect of hormone replacement on bone fracture and colorectal cancer, the incidence of... tovább »

Lege Artis Medicinae

MAY 21, 2006

[MEDICINAL HERBS IN THE TREATMENT OF LIVER DISEASES]

SCHULLER János

[Today, alternative medicine is increasingly popular among patients. Patients with liver diseases surprisingly often use complementary treatment, mainly medicinal herbs, with or without the knowledge of their physician. This is one of the reasons why doctors may not ignore alternative medicine. Another reason is that twenty to thirty percent of medicaments now used in conventional therapy were originally produced from herbs. This means that some of the herbal medicines now applied in... tovább »

Lege Artis Medicinae

MAY 21, 2006

[CARDIOVASCULAR PREVENTION BY INHIBITION OF THE ANGIOTENSIN CONVERTING ENZYME IN VIEW OF THE RESULTS OF RECENT TRIALS]

PAPP Előd, TÓTH Kálmán

[Angiotensin converting enzyme inhibitors have long been basic drugs in the treatment of heart failure. In the preventive treatment of ischaemic heart disease, however, their mortality-reducing effect has only been proved recently. The HOPE was the first trial that showed a beneficial effect of the angiotensin converting enzyme inhibitor ramipril in patients at high risk for cardiovascular diseases. The EUROPA trial showed a positive role of perindopril in the reduction of hard clinical... tovább »

Lege Artis Medicinae

MAY 21, 2006

[NEW DATA ABOUT INFLAMMATORY MYOPATHIES]

DANKÓ Katalin, PONYI Andrea, CONSTANTIN Tamás

[Idiopathic inflammatory myopathies are systemic autoimmune diseases with an immune-mediated inflammation of the striated muscles which lead to progressive muscle weakness. Their cause is still unknown, but recently the understanding of the molecular immunopathology has improved, which may as well offer therapeutic targets in the future. The aim of this review is to present currently available data on the most important factors and processes that are involved in the pathogenesis of these... tovább »

Lege Artis Medicinae

MAY 21, 2006

[DISEASES OF THE SPINE ACCOMPANIED BY LOWER BACK PAIN]

TÓTH Edit Ágnes

[It is estimated that 80% of the adult population consult their general practitioner for lower back pain at some point in their life. Apart from family doctors all medical specialists may encounter this complaint, which makes the wide-spread knowledge of this topic desirable. Pain associated with spinal diseases has two distinct types, non-inflammatory and inflammatory pain. Non-inflammatory diseases may cause moderate pain that increases with movement or functional limitation lasting for a few... tovább »

Lege Artis Medicinae

MAY 21, 2006

Lege Artis Medicinae

MAY 21, 2006