Hypertension and nephrology

[Recent developments in the diagnosis and therapy of haemolytic uremic syndrome. Part 1: Diagnosis and initial therapy]

PROHÁSZKA Zoltán1,2, SZILÁGYI Ágnes1,2, SZABÓ Melinda Zsuzsanna oh.1, RÉTI Marienn3, REUSZ György4

OCTOBER 20, 2010

Hypertension and nephrology - 2010;14(05)

[In this summary an overview is offered on the recent developments of the investigation and the treatment of hemolytic uremic syndrome. Based on the recent developments in the understanding of the pathogenesis and on the novel diagnostics there is an increasing ability to identify the etiology of specific diagnostic sub-groups of the disease. This molecular etiology-based classification and sub-group diagnosis has substantial influence on the short-term and long-term management of the affected patients. The first part of our review focuses on the steps of first and second line diagnosis and the selection between available therapeutic options, and provides flow-charts for the daily work. The various aspects of the long-term management and disease monitoring in hemolytic uremic syndrome will be reviewed in a second article in the future.]

AFFILIATIONS

  1. Semmelweis Egyetem, Általános Orvostudományi Kar, III. sz. Belgyógyászati Klinika, Kutatólaboratórium, Budapest
  2. MTA-SE, Gyulladásbiológiai és Immungenomikai Kutatócsoport, Budapest
  3. Fôvárosi Önkormányzat, Egyesített Szent István és Szent László KórházRendelôintézet, Hematológiai és Ôssejt-transzplantációs Osztály, Apheresis és Ôssejt-feldolgozó Részleg, Budapest
  4. Semmelweis Egyetem, Általános Orvostudományi Kar, I. sz. Gyermekgyógyászati Klinika, Nefrológiai Osztály, Budapest

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