Hypertension and nephrology

[Nonproteinuric diabetic kidney disease]

LENGYEL Zoltán1, SCHANDL László2

DECEMBER 20, 2021

Hypertension and nephrology - 2021;25(06)

DOI: https://doi.org/10.33668/hn.25.029

[Diabetic nephropathy is one of the most common causes of chronic kidney disease. In recent years, besides the classic phenotype with increased urinary albumin excretion, another phenotype showing Progressive kidney failure without albuminuria has been observed with increasing frequency. The histology, the pathophysiology and the course of non-proteinuric diabetic kidney disease differs from the classic phenotype in several respects. The former shows traits similar to atherosclerotic kidney disease with respect to association with cardiovascular disease and histological alterations and the progression is slower. This has important implications concerning the screening, treatment and prognosis of the disease. While the available data about non-proteinuric diabetic nephropathy is relatively scant, it deserves attention both in everyday clinical practice and in scientific research.]


  1. Szent Margit Kórház, IV. Belgyógyászati Osztály, Budapest
  2. Észak-közép-budai Centrum, Új Szent János Kórház és Szakrendelő, II. Belgyógyászati-Diabetológiai Osztály, Budapest



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