Hungarian Radiology

[Honours from the Society of Hungarian Radiologists, 2003]

AUGUST 20, 2003

Hungarian Radiology - 2003;77(04)

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Hungarian Radiology

[New perspectives in ultrasound diagnostics Interview with professor William Lees]

HARKÁNYI Zoltán

Hungarian Radiology

[Our experiences with the use of phosphor plate X-ray system and PACS]

BARTA H. Miklós, BERENTEY Ernő, FORNET Béla, FORRAI Gábor

[In this study the experiences, the advantages and disadvantages of a full digital radiology department are presented. The conventional radiology and the spot films of gastroenterologic studies are exposed on phosphor plates since 1999 at our department. Two work-stations are used for making the reports and six viewing-stations are installed at distant departments. A central server organizes the data and pictures flow and the archive system consists of magnetooptical discs in a juke-box. The conventional X-ray methods are fully integrated in the system. The number of hardcopies is dramatically decreased. The clinicians may easily access the images on the viewingstations. Possibility of teleradiology and teleconsultation is integrated in the system. The quality of the examinations is improved and became uniform. The images of different methods (CT, fluoroscopy) are stored also in digital format. The disadvantages are the high cost of installation, a new workflow and reporting habits must be initiated. A problem of one element can cause the breakdown of the whole system. The new technics, the digital world forces us to develope and define new technical standards in order to obtain uniform quality.]

Hungarian Radiology

[Follow-up of infants undergoing pyeloplasty: renal ultrasound and diuresis renography changes]

KIS Éva, NYITRAI Anna, VÁRKONYI Ildikó, BÁRTFAI Katalin, GYÖRKE Tamás, MÁTTYUS István, VEREBÉLY Tibor

[INTRODUCTION - The authors reviewed their experience after pyeloplasty in infants, according to the follow-up results of ultrasound and nuclear renography. PATIENTS AND METHODS - During the period 1988-2001 184 infants underwent pyeloplasty for ureteropelvic junction (UPJ) obstruction. Patients (n=91) with unilateral UPJ obstruction and normal contralateral kidney were included in this study. Patients ages at surgery were between 1 day-36 months. Preoperative evaluation included ultrasound examinations and diuretic renograms. Follow-up ultrasound examinations were done after 3, 6, 12 months, later yearly. Depending on the result of the ultrasound examination isotope scan were done. RESULTS - The pelviureteric obstruction were detected prenatally at 65 cases (71%). Preoperative ultrasound revealed grade 3-4 pyelocaliectasis in all patients. All patients had obstruction on preoperative renography, nine kidneys had no function, in 37 cases (41%) hydronephrotic kidneys had diminished function. Nine patients underwent nephrectomy because of non-functioning kidney. Eighty two infants underwent pyeloplasty. Grade of hydronephrosis improved in 56% of kidneys and dilatation was the same one year after pyeloplasty in 44% of kidneys. Five years after pyeloplasty 91% of kidneys, after eight years 97% of hydronephrosis improved or cured. Postoperative renography showed improvement in drainage in all preoperatively obstructed kidneys. The renal function improved only in 22% of cases at the end of the first postoperative year, and no further improvement were detected later on. CONCLUSION - Pyeloplasty in infant ages significantly cured the drainage early after surgery. The resolution of hydronephrosis is relatively slow, but after eight years dilatation cured or improved in most of the affected kidneys. Improvement of the renal function was detected only in small part of the cases.]

Hungarian Radiology

[Radial scar associated with lobular neoplasia in the breast]

ERDŐSI Éva, HERTELENDY Ágnes, GREXA Erzsébet, ANGA Béla, VARGA Zoltán

[INTRODUCTION - The authors are presenting the case of a 55-year-old female patient with breast abnormalities of unclear morphology. CASE REPORT - The lesion seen in the left breast was characteristic of radial scar in which, however, numerous, but not clearly benign microcalcifications were detected. During histological examination a radial scar associated with a small lobular neoplasia was diagnosed. However, these microcalcifications were not related to the malignancy. CONCLUSION - In radial scar extensive benign microcalcifications may develop. Nevertheless we should bear in mind that in 10-30% of cases this disorder can be associated with malignancy even without mammographic signs. The final diagnosis, however, should always be made on the basis of histological examination.]

Hungarian Radiology

[Radiotherapy]

GYENES György

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[Advanced Parkinson’s disease characteristics in clinical practice: Results from the OBSERVE-PD study and sub-analysis of the Hungarian data]

TAKÁTS Annamária, ASCHERMANN Zsuzsanna, VÉCSEI László, KLIVÉNYI Péter, DÉZSI Lívia, ZÁDORI Dénes, VALIKOVICS Attila, VARANNAI Lajos, ONUK Koray, KINCZEL Beatrix, KOVÁCS Norbert

[The majority of patients with advanced Parkinson’s disease are treated at specialized movement disorder centers. Currently, there is no clear consensus on how to define the stages of Parkinson’s disease; the proportion of Parkinson’s patients with advanced Parkinson’s disease, the referral process, and the clinical features used to characterize advanced Parkinson’s disease are not well delineated. The primary objective of this observational study was to evaluate the proportion of Parkinson’s patients identified as advanced patients according to physician’s judgment in all participating movement disorder centers across the study. Here we evaluate the Hungarian subset of the participating patients. The study was conducted in a cross-sectional, non-interventional, multi-country, multi-center format in 18 countries. Data were collected during a single patient visit. Current Parkinson’s disease status was assessed with Unified Parkinson’s Disease Rating Scale (UPDRS) parts II, III, IV, and V (modified Hoehn and Yahr staging). Non-motor symptoms were assessed using the PD Non-motor Symptoms Scale (NMSS); quality of life was assessed with the PD 8-item Quality-of-Life Questionnaire (PDQ-8). Parkinson’s disease was classified as advanced versus non-advanced based on physician assessment and on questions developed by the Delphi method. Overall, 2627 patients with Parkinson’s disease from 126 sites were documented. In Hungary, 100 patients with Parkinson’s disease were documented in four movement disorder centers, and, according to the physician assessment, 50% of these patients had advanced Parkinson’s disease. Their mean scores showed significantly higher impairment in those with, versus without advanced Parkinson’s disease: UPDRS II (14.1 vs. 9.2), UPDRS IV Q32 (1.1 vs. 0.0) and Q39 (1.1 vs. 0.5), UPDRS V (2.8 vs. 2.0) and PDQ-8 (29.1 vs. 18.9). Physicians in Hungarian movement disorder centers assessed that half of the Parkinson’s patients had advanced disease, with worse motor and non-motor symptom severity and worse QoL than those without advanced Parkinson’s disease. Despite being classified as eligible for invasive/device-aided treatment, that treatment had not been initiated in 25% of these patients.]

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Evaluation of anxiety, depression and marital relationships in patients with migraine

DEMIR Fıgen Ulku, BOZKURT Oya

Aim - The aim of this study was to evaluate the frequency and characteristics of attacks in patients with migraine, to determine the effects of anxiety or depressive symptoms, and to evaluate the marital relationships of patients with migraine. Method - Thirty patients who were admitted to the neurology outpatient clinic of our hospital between July 2018 and October 2018 and were diagnosed with migraine according to the 2013 International Headache Society (IHS) diagnostic criteria were included in this cross-sectional study. Age, sex, headache frequency and severity, depressive traits, marital satisfaction and anxiety status were examined. We used the Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Maudsley Marital Questionnaire (MMQ) and Visual Analogue Scale (VAS) for measuring relevant parameters. Results - The mean severity of migraine pain according to VAS scale was 6.93 ± 1.41 and the mean number of migraine attacks was 4.50 ± 4.24. The mean BDI score of the patients was 12.66 ± 8.98, the mean MMQ-M score was 19.80 ± 12.52, the mean MMQ-S score was 13.20 ± 9.53, the mean STAI-state score was 39.93 ± 10.87 and the mean STAI-trait score was 45.73 ± 8.96. No significant correlation was found between age, number of migraine attacks, migraine duration, migraine headache intensity, and BDI, STAI and MMQ scores (p>0.05). But there was a positive correlation between MMQ-S and scores obtained from the BDI and STAI-state scales (p<0.05). Conclusion - In this study more than half of the migraine patients had mild, moderate or severe depression. A positive correlation was found between sexual dissatisfaction and scale scores of depression and anxiety.

Clinical Oncology

[Complications of infusion treatment with emphasis on extravasation of cytostatics]

HARISI Revekka

[The extravasation of cytostatics is the most signifi cant complication of infusion therapy in cancer treatment. Extravasation refers to the inadvertent infi ltration of cytostatic drugs into subcutaneous or subdermal tissues surrounding the intravenous or intraarterial administration site. According to literature data incidence estimates between 0,01-7%. Extravasated drugs are classifi ed according to their potential for causing damage as vesicant, irritant and nonvesicant. Knowledge of risk factors, the patientrelated and treatment-related ones is important to minimize the occurrence of extravasation. In order to reduce the risk of extravasation, the staff involved in the tumor infusion therapy must be specially trained to implement several preventive and therapeutical protocols. In 2012, ESMO-EONS has put together a new comprehensive treatment protocol on the topic of cytostatics extravasation. Protocol recommended that every oncological department, who administers chemotherapy have to have extravasation trained team and a standby extravasation kit. According to the new ESMO-EONS guideline subcutaneous corticoids are not recommended, anymore. In case of mechloretamine extravasation the recommendation is immediate subcutaneous injection of sodium thiosulfate. After extravasation of anthracyclines, mitomycin C and platin salts the best treatment opportunity is subcutan dimethyl sulfoxide administration. In case of anthracyclines’ extravasation intravenous dexrazoxane treatment is also effective. Hyaluronidase, injected into or under the skin, facilitates absorption of extravasated drugs because of increases connective tissue permeability, promotes the spreading and reduces the local concentration of the extravasated citostatic agents. Hyaluronidase might be effi cacious in preventing skin necrosis by extravasation due to vinca alkaloids. The treatment of unresolved tissue necrosis or pain lasting more than 10 days is surgical debridement. Because of the medical and juristic importance of the extravasation event, it is necessary to establish uniform guidelines for treatment of extravasation, in all Hungarian Oncological Centers.]

Clinical Neuroscience

[Decisional collisions between evidence and experience based medicine in care of people with epilepsy]

RAJNA Péter

[Background – Based on the literature and his long-term clinical practice the author stresses the main collisions of evidence and experience based medicine in the care of people with epilepsy. Purpose – To see, what are the professional decisions of high responsibility in the epilepsy-care, in whose the relevant clinical research is still lacking or does not give a satisfactory basis. Methods – Following the structure of the Hungarian Guideline the author points the critical situations and decisions. He explains also the causes of the dilemmas: the lack or uncertainty of evidences or the difficulty of scientific investigation of the situation. Results – There are some priorities of experience based medicine in the following areas: definition of epilepsy, classification of seizures, etiology – including genetic background –, role of precipitating and provoking factors. These are able to influence the complex diagnosis. In the pharmacotherapy the choice of the first drug and the optimal algorithm as well as the tasks during the care are also depends on personal experiences sometimes contradictory to the official recommendations. Same can occur in the choice of the non-pharmacological treatments and rehabilitation. Discussion and conclusion – Personal professional experiences (and interests of patients) must be obligatory accessories of evidence based attitude, but for achieving the optimal results, in some situations they replace the official recommendations. Therefore it is very important that the problematic patients do meet experts having necessary experiences and also professional responsibility to help in these decisions. ]

Clinical Neuroscience

[12th Annual Meeting of the Hungarian Society of Neuroradiology]