Clinical Oncology - 2021;8(4)

Clinical Oncology

NOVEMBER 30, 2021

[Gastrointestinal cancers: role of biomarkers and based on driven treatment of gastrointestinal cancers]

PAJKOS Gábor

[Remarkable advancements in techniques of genomic profiling and bioinformatics have led to the precision medicine in oncology approach, targeted therapy and immune checkpoint inhibitors achieved radically change in treatment efficacy based on accumulation of knowledge on the genomic profiles of gastrointestinal tract cancer (GI). Advanced or disseminated poor risk GI cancer patients have had a better chance for that progression free and/or overall survival. Highly effective treatment needs to... tovább »

Clinical Oncology

NOVEMBER 30, 2021

[Microbiome and cancer]

MIKÓ Edit, BAI Péter

[Most compartments and organs of the human body are not sterile, bacterial DNA and RNA can be detected using next generation sequencing techniques. All bacterial DNA in a compartment is called the metagenome, all bacterial transcripts are termed metatranscriptome, while all bacterial species is coined the microbiome. The microbiome transforms in neoplastic diseases that is called the oncobiome. Most tumors are colonized by bacteria that supports tumor growth and development. Microbiome... tovább »

Clinical Oncology

NOVEMBER 30, 2021

Clinical Oncology

NOVEMBER 30, 2021

[Mechanisms of metastasis formation as potential therapeutic targets]

TÍMÁR József, SEBESTYÉN Anna, KOPPER László

[The end-stage of the tumor progression is the development of the metastatic disease. The biological basis of this progression is well known, however the exact molecular background of it is not. In this process the metastatic cancer cells develop maximal adaptation to extreme environmental clues and collaborative potential with wide array of host cells, accordingly the metastatization takes place in an organ specific manner. The metastases are different from the primary tumor but from each... tovább »

Clinical Oncology

NOVEMBER 30, 2021

[The concept and use of placebo and nocebo in oncology]

VÉGH Éva, BAKI Márta

[Placebo and nocebo effects recognised through all of the history of medicine, and these effects can be found also in the field of oncology research and clinical practice. Placebo effect are more than the effects of an inert substance. Placebo benefits the health status because of the person’s belief and nocebo worsens the health status of the patient. Several psychological mechanisms are involved in placebo/nocebo effects; expectation, learning processes (classical conditioning and... tovább »

Clinical Oncology

NOVEMBER 30, 2021

[Health benefits of a widely available form of hypnosis – based psychological support at each stage of the oncology clinical pathway]

SOMOGYI Erika, ZSENI Annamária

[Over the past three decades, several studies adopting a complex biopsychosocial approach to disease and medicine examined the health benefits of hypnosis-based techniques at various stages of the oncology clinical pathway. The obtained findings consistently demonstrate that the psychological support provided in hypnosis has measurable and replicable benefits in improving oncological patients’ quality of life by reducing the distress, pain and adverse effects accompanying various oncological... tovább »