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Clinical Oncology - 2020;7(3)
Content
Clinical Oncology
AUGUST 28, 2020
Clinical Oncology
AUGUST 28, 2020
[The hormonal therapy of breast cancer]
[Breast cancer will be diagnosed in 12% of women in well-developed countries over the course of their lifetimes. This review focus on current approaches and strategies of systemic endocrine therapy of breast cancer. Breast cancer can be divided into three main subgroups based on the presence and absence of molecular markers (ER, PR, HER2 receptors). For patients without metastases the therapeutic goals are preventing the locoregional and distant recurrence. The length of adjuvant hormonal... tovább »
Clinical Oncology
AUGUST 28, 2020
[Complex treatment of head and neck cancers – overview]
[Treatment of head and neck squamous cell carcinomas (HNSCC) is exceptionally complex, requiring the close cooperation of the head and neck surgeon, radiation oncologist and medical oncologist. Excellent tumor control should be our primary goal, however, the selection of treatment should not only be guided by oncologic radicality but by the need of satisfactory quality of life (as most local therapies affect respiratory, swallowing and/or speech function), too. Based on the appropriate... tovább »
Clinical Oncology
AUGUST 28, 2020
Clinical Oncology
AUGUST 28, 2020
[Importance of hypoxia in tumor progression: road to Nobel price and novel therapeutic opportunities]
[It is now evident that cancer hypoxia is one of the new hallmark of cancer due to its consequences in gene expression, metabolism and biology. The importance of cancer hypoxia was recognized by the Nobel-price award in 2019. There are three major causes of cancer hypoxia: insuffi cient vascularization, systemic hypoxia of the host and constitutive activation of oncogene driven signaling pathways, all leading to a unique form of genetic reprogramming by HIF transcription factors. The... tovább »
Clinical Oncology
AUGUST 28, 2020
[The use of vitamins and trace elements in oncology]
[The effects of diet on development cancer and tumor control has been studied for along time, because diet has a key role in treatment of cancer. A multidisciplinary team is needed for proper use of vitamins and trace elements in cancer patients. This multidisciplinary team (oncologist, dietitian, laboratory assistant) can provide the professional supervision from the medical examination to the practical implementation, which can control the proper intake of these nutrients and the individual... tovább »
Clinical Oncology
AUGUST 28, 2020
[The indication for surgical resection in secondary liver malignancies - New therapeutic approaches]
[During the last decade liver surgery underwent major improvement: mortality rates reduced meanwhile new surgical approaches converted surgeons’ consideration on many advanced cases likely to be resectable. Liver is the most frequent site for tumor metastases and liver metastasis surgery experienced major changes as well. As long as liver resection related mortality rates have decreased indication for operative treatment of liver metastasis with certain primary tumors (stomach, pancreas) gained... tovább »
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Clinical Neuroscience
Cases of inborn errors of metabolism diagnosed in children with autism
18. JAN
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Clinical Neuroscience
Evaluation of the effectiveness of transforaminal epidural steroid injection in far lateral lumbar disc herniations
18. JAN
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Clinical Neuroscience
Electrophysiological investigation for autonomic dysfunction in patients with myasthenia gravis: A prospective study
18. JAN
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Lege Artis Medicinae
[LAM 30: 1990–2020. Facing the mirror: Three decades of LAM, the Hungarian medicine and health care system]
11. DEC
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