Clinical Neuroscience

[The absence of the common LRRK2 G2019S mutation in 120 young onset Hungarian Parkinon’s disease patients]

BALICZA Péter1, BEREZNAI Benjámin1, TAKÁTS Annamária1, KLIVÉNYI Péter2, DIBÓ György2, HIDASI Eszter3, BALOGH István4, MOLNÁR Mária Judit1

JULY 30, 2012

Clinical Neuroscience - 2012;65(07-08)

[Parkinson’s disease is a promising target of applying personalized medicine. For this purpose it is crucial to reveal the genetic and environmental factors, which contribute to the disease, also to collect epidemiologic data and to preserve the patients samples and data in a proper biobank. In our investigation we examined the prevalence of the most frequent Parkinson’s disease causing LRRK2 G2019S mutation in a Hungarian Parkinson-patient group. From 120 patients, we haven’t detected this substitution in anyone. Our investigation suggest that the mutation LRRK2 G2019S may be a rare cause of Parkinson disease in the Hungarian population.]


  1. Semmelweis Egyetem, Neurológiai Klinika, Molekuláris Neurológiai Klinikai és Kutatási Központ, Budapest
  2. Szegedi Tudományegyetem, Neurológiai Klinika, Szeged
  3. Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Neurológiai Klinika, Debrecen
  4. Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Klinikai Biokémiai és Molekuláris Patológiai Intézet, Debrecen



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