Clinical Neuroscience

[Panic disorder: data on one of the anxiety disorders described form ]

KECSKEMÉTY Péter1, FALUDI Gábor1

JANUARY 01, 1985

Clinical Neuroscience - 1985;38(01)

[The authors review the problem of panic disorder based on the recommendations of DSM-III. They analyse this well-defined form of anxiety from the perspective of literature and their own experience. It is concluded that it is a disease entity with specific endogenous characteristics, probably biologically and genetically based, and that this seems to be confirmed by favourable chemosensitivity. Its recognition is important in view of the prevalence of the disease, its unusually high mortality and the efficacy of targeted treatment in the face of a severe morbidity of untreated cases.]

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  1. Fővárosi János Kórház-Rendelőintézet Mentalhygiéniás Osztálya

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Further articles in this publication

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[Misdiagnosis of multiple sclerosis]

PÁLFFY György

[The author presents 7 patients with spinal and 7 patients with intracranial space-occupying disease, whose disease was considered to be multiple sclerosis for a shorter or longer period of time, and 2 patients with multiple sclerosis, whose disease was not recognized. For these 16 patients, he analyses the clinical and CSF symptoms and neuroradiological examination procedures that can protect the physician from these errors.]

Clinical Neuroscience

[Cavity irradiation treatment of craniopharyngeoma cysts with 90 yttrium silicate colloid]

JULOW Jenő, LÁNYI Ferenc, HAJDA Márta, SIMKOVICS Miklós, ARANY Ilona, TÓTH Szabolcs, PÁSZTOR Emil

[ The authors report on the cavity radiotherapy of craniopharyngeoma cysts in 9 patients with 90Yttrium silicate colloid. The method has been used at the National Institute of Neurosurgical Sciences since 1975. In the vast majority of cases, the procedure results in shrinkage of the craniopharyngeal cysts, and in optimal cases, their disappearance, followed in most cases by improvement of the patients' condition. ]

Clinical Neuroscience

[Differential diagnostic indices in the MMPI test for the differentiation of neuroses ]

PRESSING Lajos

[Using the mathematical model of discriminant analysis, we have developed optimal linear combinations of MMPI scales that can differentiate neurosis from other core diagnostic categories-psychosomatic disorders, personality disorders, and psychoses-with the highest possible efficiency. The patient study sample of 940 patients allowed us to verify the validity of the indicators in independent groups. The indicators can be used as a differential diagnostic reference in practical diagnostic work. ]

Clinical Neuroscience

[Szikla Gábor (1928-1983)]

CSANDA Endre

Clinical Neuroscience

[Report on a study trip to the Netherlands]

OZSVÁTH Károly

[In the framework of the Dutch-Hungarian cultural and scientific agreement, I studied Dutch psychiatric care from 27 September to 11 October 1983. 1. the general characteristics of mental health care; 2. the hierarchy: health care, including psychiatric care, is divided into three stages; 3. the democratization of psychiatric care]

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We aimed to investigate the association between fluoxetine use and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients. This retrospective case-control study used data extracted from the medical records of adult patients hospitalised with moderate or severe COVID-19 pneumonia at the Uzsoki Teaching Hospital of the Semmelweis University in Budapest, Hungary between 17 March and 22 April 2021. As a part of standard medical treatment, patients received anti-COVID-19 therapies as favipiravir, remdesivir, baricitinib or a combination of these drugs; and 110 of them received 20 mg fluoxetine capsules once daily as an adjuvant medication. Multivariable logistic regression was used to evaluate the association between fluoxetine use and mortality. For excluding a fluoxetine-selection bias potentially influencing our results, we compared baseline prognostic markers in the two groups treated versus not treated with fluoxetine. Out of the 269 participants, 205 (76.2%) survived and 64 (23.8%) died between days 2 and 28 after hospitalisation. Greater age (OR [95% CI] 1.08 [1.05–1.11], p<0.001), radiographic severity based on chest X-ray (OR [95% CI] 2.03 [1.27–3.25], p=0.003) and higher score of shortened National Early Warning Score (sNEWS) (OR [95% CI] 1.20 [1.01-1.43], p=0.04) were associated with higher mortality. Fluoxetine use was associated with an important (70%) decrease of mortality (OR [95% CI] 0.33 [0.16–0.68], p=0.002) compared to the non-fluoxetine group. Age, gender, LDH, CRP, and D-dimer levels, sNEWS, Chest X-ray score did not show statistical difference between the fluoxetine and non-fluoxetine groups supporting the reliability of our finding. Provisional to confirmation in randomised controlled studies, fluoxetine may be a potent treatment increasing the survival for COVID-19 pneumonia.

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