[Vaccines against COVID-19 pandemic]
FALUS András1, SZEKANECZ Zoltán2
FEBRUARY 20, 2021
Lege Artis Medicinae - 2021;31(01-02)
DOI: https://doi.org/10.33616/lam.31.002
Review
FALUS András1, SZEKANECZ Zoltán2
FEBRUARY 20, 2021
Lege Artis Medicinae - 2021;31(01-02)
DOI: https://doi.org/10.33616/lam.31.002
Review
Szöveg nagyítása:
[The rapidly spreading SARS-CoV2 respiratory virus has evoked an epidemic with serious aftermath around the world. In addition to the health effects, the global economic damage is actually unpredictable. At the same time, the pandemic has launched a series of unprecedented collaborative scientific research, including the development of vaccines. This study summarizes up-to-date information on vaccines, immune memory, and some emerging clinical effects.]
Lege Artis Medicinae
[Invasive investigations show that in two-thirds of patients the myocardial ischaemia persists without obstructive coronary disease and any other heart conditions (INOCA). The underlying cause may be microvascular dysfunction (CMD) with consecutive microvascular coronary disease (MVD) and microvascular or epicardial vasospastic angina (MVA). The modern practice of clinical cardiology while using the developed non-invasive cardiac imaging permits exact measuring of the coronary flow with its characteristic indices. All of these improve the diagnosing of CMD-induced myocardial ischemia and provide opportunity to determine primary MVD cases. Since the recognition and treatment of MVD is significantly underrepresented in the Hungarian medical care, the primary stable microvascular angina (MVA) is described in detail below with its modern invasive and non-invasive differential diagnosis and treatment, concerning especially its frequency provoked by high blood pressure and female coronary heart diseases. There are highlighted all recommended diagnostic procedures available under domestic conditions.]
Lege Artis Medicinae
[Deterioration of social functions and quality of life and lower level of satisfaction with life are often joining to axiety disorders. Considering the higher prevalence rates across anxiety disorders for women, the aim of this study was to examine the relationship of social phobia with trait anxiety, perfectionism, use of pharmaceuticals, self-efficacy and life satisfaction in a group of young female participants. Online, self-administered questionnaire was used as a method of data collection at different social network sites. The sample consisted of young women aged between 14–35 years (N = 435, M = 27.3 years; SD = 5.9). The questionnaire contained items of socio-demographic variables, use of pharmaceuticals as well as mental background variables (Social Phobia Inventory, State-Trait Anxiety Inventory, Multidimensional Perfectionism Scale, General Perceived Self-Efficacy Scale, Satisfaction with Life Scale). Besides correlation analysis, cluster analysis was conducted. rait anxiety shows strong correlation with social phobia, perfectionism and use of pharmaceuticals. After examining all variables three clusters were emerging: 1) high level of trait anxiety with social phobia, moderate perfectionism, low levels of self-effcacy and satisfaction with life; 2) trait anxiety below the average without social phobia, high self-efficacy and satisfaction with life; 3) trait anxiety above the average with moderate phobia, high perfectionism with high self-efficacy and moderate life satisfaction. Results of our study show that social phobia strongly interrelates not only with trait anxiety as a stable part of personality but with self-estimated lower well-being and lack of mental protective factors. ]
Lege Artis Medicinae
[Chronic obstructive pulmonary disease (COPD) is prognosticated to become the 3rd most prevalent cause of early lethality. It’s main etiology is long-term smoking which induces chronic inflammation and obstruction of the airways as well as elastolysis of the pulmonary interstitium which lead to emphysema. Increased resistance of the intrathoracic airways and emphysema induce hyperinflation of the lung and chest which increases the work-load of the respiratory muscles. COPD patients are typically hypoxaemic and normocapnic. Finally, fatigue of the respiratory muscles cause the development of global respiratory failure (hypercapnia and severe hypoxaemia). Most effective intervention is smoking cessation. Maintanance treatment includes inhalational long-acting bronchodilators with or without inhalational corticosteroids. Acute exacerbation is treated with O2 supplementation, inhalational bronchodilators, systemic steroids and/or antiobiotics. Frequency and severity of acute exacerbations prognosticate shorter survival. In chronic respiratory failure long-term home O2 therapy can be provided.]
Lege Artis Medicinae
[Abstract in english is not available.]
Lege Artis Medicinae
[ ]
Journal of Nursing Theory and Practice
[The events of the SARS-COV-19 pandemic have highlighted the need to focus on a number of tools and methods to improve the delivery of healthcare. Telemedicine can help in this innovation. The use of telemedicine during the Covid-19 pandemic was new in our country, but has long been used abroad. International experience, as well as that we gained during the covid pandemic, shows that the methodology is worth using in the domestic health care system in the future. The primary aim of this paper is to introduce the concepts related to telehealth. A sub-objective is to briefly review international practice. With our study we want to help to increase the knowledge of health professionals about telemedicine.]
Clinical Neuroscience
Long Covid is a complex condition characterised by symptoms that persist for weeks and months after the Covid infection, accompanied by cognitive impairment that negatively affects daily life. Understanding this complex condition is important for the development of diagnostic and therapeutic strategies. This article aims to provide a comprehensive overview of cognitive impairment in long-COVID.
Clinical Neuroscience
To evaluate the long-term effects of the COVID-19 pandemic on seizure frequency and levels of mental distress in individuals with epilepsy and identify potential risk factors associated with increased seizure frequency. This is a cross-sectional study conducted in Türkiye in May 2021 by phone. Information on epilepsy syndromes, antiseizure medications, average seizure frequency, and drug resistance was obtained from medical records.
Lege Artis Medicinae
[A significant number of studies addresses the benefits of high-flow nasal oxygen therapy (HFNO) in respiratory failure caused by Covid-19. However, the number among them about its use outside the intensive care unit is much less. Our study aims to evaluate the HFNO treatment data of patients with respiratory failure caused by Covid-19 in non-intensive care settings, and to compare them with three international studies and one local study with resembling subject.
To this retrospective cohort study, we selected patients with respiratory failure (n = 47) caused by Covid-19 pneumonia who were treated at the wards of the Sub-intensive Infectious Diseases Department, at Tolna County Balassa János Hospital, between March 16, and May 31, 2021. Exclusion criteria of starting HFNO therapy were low GCS (<13), multiple organ failure requiring intensive therapy, and hypercapnia (paCO2 > 50 mm Hg). With the patients’ general demographic data, we also evaluated treatment outcomes and mortality. We compared the duration of treatment and the average number of days of hospital stay with the number of care days among other patients not treated with HFNO, during the span of the study and the previous wave of the pandemic.
The patients’ mean age was 66 years (median: 67). The average duration of HFNO treatment was 6.829 days, which means a sum of 321 treatment days for 47 patients. 45% of the patients could be discharged home, 25% had to be transferred to the intensive care unit because they needed invasive ventilation, which was determined by a modified version of the national early warning score (NEWS) point system. Mortality during treatment was 30% and those of patients transferred to the intensive care unit mounted to 83%.
Compared with other three international studies and one local study, further based on our own experience, HFNO has proven to be effective in the treatment of patients with respiratory insufficiency not associated with hypercapnia caused by severe Covid-19. Based on patient feedback and nursing documentation, it increased the patient comfort compared with conventional oxygen therapy devices. Compared with data collected in the previous pandemic wave, the HFNO therapy reduced the average number of hospital treatment days and reduced the burden of the intensive care unit too.]
Effect of COVID-19 on seizures and patient behavior in people with epilepsy
Impact of COVID-19 on neurotrauma cases, mortality rates, and rebound effect: a monocenter retrospective study
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Clinical Neuroscience
Is there any difference in mortality rates of atrial fibrillation detected before or after ischemic stroke?2.
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