Lege Artis Medicinae

[THE ROLE OF STATINS IN THE MANAGEMENT OF PATIENTS WITH ARTERIAL HYPERTENSION]

VÁLYI Péter

APRIL 21, 2006

Lege Artis Medicinae - 2006;16(04)

[Hypertension and hypercholesterolemia are two very important risk factors of cardiovascular diseases. Statins are the most widely used drugs to treat hypercholesterolemia, and they also modify the efficiency of antihypertensive treatment in patients with hypertension. With the use of statins, a significant reduction in blood pressure has been described both in patients previously untreated and in patients already being treated with antihypertensive drugs. The blood pressure lowering effect of statins is partially independent of their effects on the lipid profile, and is probably related to their interaction with endothelial function, angiotensin-II receptor and other biologically important systems. The ability of statins to improve blood pressure control should be more widely considered when thinking of the complex prevention of cardiovascular diseases.]

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